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Article
Open AccessFar-infrared therapy promotes exercise capacity and glucose metabolism in mice by modulating microbiota homeostasis and activating AMPK
The benefits of physical exercise on human health make it desirable to identify new approaches that would mimic or potentiate the effects of exercise to treat metabolic diseases. However, whether far-infrared ...
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Article
The Effect of Irradiation Combined with Sodium Hydroxide Pretreatment on Component, Structure, Utilization Efficiency of Phragmites Australis
Phragmites australis (Reed) is an excellent lignocellulosic crop for bioethanol production, but its recalcitrant structure affects utilization efficiency. Therefore, the effective pretreated method to destroy the...
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Article
Open AccessA three-dimensional quantitative assessment on bony growth and symmetrical recovery of mandible after decompression for unicystic ameloblastoma
Unicystic ameloblastoma (UAM) of the jaw can be effectively reduced in volume through decompression, which promotes bone regeneration and restores jaw symmetry. This study quantitatively evaluated changes in m...
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Article
Realizing high thermoelectric performance flexible free-standing PEDOT:PSS/Bi0.5Sb1.5Te3 composite films for power generation
Flexible thermoelectrics provide a distinct solution for develo** sustainable and portable power supplies. Inorganic/organic material compositing is an effective strategy to induce a significant enhancement ...
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Article
A Comprehensive Multivariate Wind Speed Forecasting Model Utilizing Deep Learning Neural Networks
Predicting wind speed accurately is essential for the efficient generation of wind power. To enhance the precision of wind speed forecasting, this paper proposes a multivariate combinatorial model based on a d...
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Article
Hot technology and technical evolution of polypeptide nanotechnology in medical application field based on patent data analysis
The design of nanostructures based on peptides has attracted wide attention, especially the design of new nanomaterials with higher levels of multifunctional ability is gradually needed. Patent layout allows t...
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Article
Open AccessRegio- and stereoselective access to highly substituted vinylphosphine oxides via metal-free electrophilic phosphonoiodination of alkynes
In general, the P-centered ring-opening of quaternary phosphirenium salts (QPrS) predominantly leads to hydrophosphorylated products, while the C-centered ring-opening is primarily confined to intramolecular n...
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Article
Open AccessNested attention network based on category contexts learning for semantic segmentation
The attention mechanism is widely used in the field of semantic segmentation, due to the fact that it can be used to obtain effective long-distance dependencies by assigning different weights to objects accord...
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Article
Application of nanoscale metal–organic frameworks in tumor immunotherapy
Immunotherapy has attracted wide attention because it can not only kill tumor cells but also effectively prevent tumor recurrence. However, due to the poor efficacy of the monotherapy in tumor immunotherapy, c...
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Article
Perspectives on the involvement of the gut microbiota in salt-sensitive hypertension
Salt-sensitivity hypertension (SSH) is an independent predictor of cardiovascular event-related death. Despite the extensiveness of research on hypertension, which covers areas such as the sympathetic nervous ...
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Article
Open AccessCoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels
Genetic testing is crucial for precision cancer medicine. However, detecting multiple same-site insertions or deletions (indels) is challenging. Here, we introduce CoHIT (Cas12a-based One-for-all High-speed Is...
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Article
Open AccessCorrection: In vivo axial load-share ratio measurement using a novel hexapod system for safe external fixator removal
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Article
Texture and Se vacancy optimization induces high thermoelectric performance in Bi2Se3 flexible thin films
Bi2Se3-based flexible thin film with high thermoelectric performance is promising for the waste heat recovery technology. In this work, a novel post-selenization method is employed to prepare n-type Bi2Se3 flexib...
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Article
Identification, Characterization, and Computer-Aided Rational Design of a Novel Thermophilic Esterase from Geobacillus subterraneus, and Application in the Synthesis of Cinnamyl Acetate
Investigation of a novel thermophilic esterase gene from Geobacillus subterraneus DSMZ 13552 indicated a high amino acid sequence similarity of 25.9% to a reported esterase from Geobacillus sp. A strategy that in...
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Article
Computer-aided rational design strategy based on protein surface charge to improve the thermal stability of a novel esterase from Geobacillus jurassicus
Although Geobacillus are significant thermophilic bacteria source, there are no reports of thermostable esterase gene in Geobacillus jurassicus or rational design strategies to increase the thermal stability of e...
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Article
Solitons, breathers and rational solutions for the (2 + 1)-dimensional Konopelchenko–Dubrovsky equation
This paper explores the Konopelchenko–Dubrovsky (KD) equation and employs Hirota’s bilinear method and Kadomtsev–Petviashvili (KP) hierarchy reduction technique to construct solitons, line breathers, rational ...
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Article
Open AccessCatalytic asymmetric synthesis of planar-chiral dianthranilides via (Dynamic) kinetic resolution
Chirality constitutes an inherent attribute of nature. The catalytic asymmetric synthesis of molecules with central, axial, and helical chirality is a topic of intense interest and is becoming a mature field o...
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Article
Open AccessDissecting hair breakage in alopecia areata: the central role of dysregulated cysteine homeostasis
In the initial stages of Alopecia Areata (AA), the predominance of hair breakage or exclamation mark hairs serves as vital indicators of disease activity. These signs are non-invasive and are commonly employed...
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Article
Open AccessSingle-cell transcriptomic landscape and the microenvironment of normal adjacent tissues in hypopharyngeal carcinoma
The cellular origin of hypopharyngeal diseases is crucial for further diagnosis and treatment, and the microenvironment in tissues may also be associated with specific cell types at the same time. Normal adjac...
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Article
Pricing Convertible Bonds with the Penalty TF Model Using Finite Element Method
In this paper, we discuss finite element methods (FEM) for solving numerically the so-called TF model, a PDE-based model for pricing convertible bonds. The model consists of two coupled Black-Scholes equations...
