Skip to main content

3 Result(s)

within Donald F. Newgreen Remove this filter Surgical Oncology Remove this filter

and

  1. Article

    Open Access

    Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells

    Epithelial-to-mesenchymal transition (EMT) promotes cell migration and is important in metastasis. Cellular proliferation is often downregulated during EMT, and the reverse transition (MET) in metastases appea...

    Honor J Hugo, Lloyd Pereira, Randy Suryadinata, Yvette Drabsch… in Breast Cancer Research (2013)

    Download PDF (2042 KB) View Article

  2. Article

    Open Access

    Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation

    A feature of epithelial to mesenchymal transition (EMT) relevant to tumour dissemination is the reorganization of actin cytoskeleton/focal contacts, influencing cellular ECM adherence and motility. This is cou...

    Honor J Hugo, Razan Wafai, Tony Blick, Erik W Thompson, Donald F Newgreen in BMC Cancer (2009)

    Download PDF (3479 KB) View Article

  3. Article

    Open Access

    Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors

    Breast carcinoma is accompanied by changes in the acellular and cellular components of the microenvironment, the latter typified by a switch from fibroblasts to myofibroblasts.

    Stephanie C Lebret, Donald F Newgreen, Erik W Thompson… in Breast Cancer Research (2007)

    Download PDF (4117 KB) View Article