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Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system

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  1. Article

    Open Access

    Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells

    Epithelial-to-mesenchymal transition (EMT) promotes cell migration and is important in metastasis. Cellular proliferation is often downregulated during EMT, and the reverse transition (MET) in metastases appea...

    Honor J Hugo, Lloyd Pereira, Randy Suryadinata, Yvette Drabsch in Breast Cancer Research (2013)

  2. Article

    Open Access

    Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation

    A feature of epithelial to mesenchymal transition (EMT) relevant to tumour dissemination is the reorganization of actin cytoskeleton/focal contacts, influencing cellular ECM adherence and motility. This is cou...

    Honor J Hugo, Razan Wafai, Tony Blick, Erik W Thompson, Donald F Newgreen in BMC Cancer (2009)

  3. Article

    Open Access

    Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors

    Breast carcinoma is accompanied by changes in the acellular and cellular components of the microenvironment, the latter typified by a switch from fibroblasts to myofibroblasts.

    Stephanie C Lebret, Donald F Newgreen, Erik W Thompson in Breast Cancer Research (2007)