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269 Result(s)
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Article
Open AccessComorbidity in myasthenia gravis: multicentric, hospital-based, and controlled study of 178 Italian patients
Myasthenia gravis (MG) is an autoimmune disorder with fluctuating weakness that causes significant disability and morbidity. Comorbidities may influence the course of MG, particularly in specific subgroups. Th...
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Open AccessPersistent COVID-19 parosmia and olfactory loss post olfactory training: randomized clinical trial comparing central and peripheral-acting therapeutics
Although COVID-19 anosmia is often transient, patients with persistent olfactory dysfunction (pOD) can experience refractory parosmia and diminished smell. This study evaluated four putative therapies for paro...
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Open AccessMidterm follow-up after embolization of intracranial aneurysms proximal to the circle of Willis with the Silk Vista flow diverter: the I-MAMA registry
The aim of this registry was to assess technical success, procedural safety and mid- to long-term follow-up results of the Silk Vista “Mama” (SVM) flow diverter (BALT, Montmorency, France) for the treatment of...
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Open AccessMigraine chronification as an allostatic disorder: a proof-of-concept study
The underpinning biologics of migraine chronification are not well understood. We aim to investigate the role of the cumulative burden of stress, namely the allostatic load, in migraine chronification.
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Open AccessNormal spinopelvic parameters and correlation analysis in 217 asymptomatic children
Understanding spinal sagittal balance is crucial for assessing and treating spinal deformities in pediatric populations.
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Open AccessCorrection to: Brand new norms for a good old test: Northern Italy normative study of MiniMental State Examination
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Open AccessValidation of the Quality Analysis of Medical Artificial Intelligence (QAMAI) tool: a new tool to assess the quality of health information provided by AI platforms
The widespread diffusion of Artificial Intelligence (AI) platforms is revolutionizing how health-related information is disseminated, thereby highlighting the need for tools to evaluate the quality of such inf...
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Open AccessSerum neurofilament light chain levels correlate with small fiber related parameters in patients with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN)
Recent evidence suggests that both serum neurofilament light chain (sNfL) levels and small fiber related diagnostic variables may be valuable disease biomarkers of hereditary transthyretin amyloidosis with pol...
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Open AccessA new perspective on positive symptoms: expression of damage or self-defence mechanism of the brain?
Usually, positive neurological symptoms are considered as the consequence of a mere, afinalistic and abnormal increase in function of specific brain areas. However, according to the Theory of Active Inference,...
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Open AccessISSLS PRIZE in Basic Science 2024: superiority of nucleus pulposus cell- versus mesenchymal stromal cell-derived extracellular vesicles in attenuating disc degeneration and alleviating pain
To investigate the therapeutic potential of extracellular vesicles (EVs) derived from human nucleus pulposus cells (NPCs), with a specific emphasis on Tie2-enhanced NPCs, compared to EVs derived from human bon...
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Open AccessPerinatal outcome in anti-NMDAr encephalitis during pregnancy—a systematic review with individual patients’ data analysis
Anti-N-methyl-D-aspartate receptor (NMDAr) antibody encephalitis is an autoimmune disorder characterized by synaptic NMDAr current disruption and receptor hypofunction, often affecting women during pregnancy. ...
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Open AccessCorrection to: Brivaracetam use in clinical practice: a Delphi consensus on its role as first add‑on therapy in focal epilepsy and beyond
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Open AccessEvaluation of an impedance-based method to monitor the insertion of the electrode array during cochlear implantation
Cochlear implantation is a prevalent remedy for severe-to-profound hearing loss. Optimising outcomes and hearing preservation, and minimising insertion trauma, require precise electrode placement. Objective mo...
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Open AccessBrivaracetam use in clinical practice: a Delphi consensus on its role as first add-on therapy in focal epilepsy and beyond
Antiseizure medications remain the cornerstone of treatment for epilepsy, although a proportion of individuals with the condition will continue to experience seizures despite appropriate therapy. Treatment cho...
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Open AccessPlasma concentrations of glial fibrillary acidic protein, neurofilament light, and tau in Alexander disease
Alexander disease (AxD) is a rare leukodystrophy caused by dominant gain-of-function mutations in the gene encoding the astrocyte intermediate filament, glial fibrillary acidic protein (GFAP). However, there i...
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Open AccessAdult-onset leukoencephalopathy with persistent diffusion restriction dot lesions
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Open AccessIntracranial complications of sinogenic and otogenic infections in children: an ESPN survey on their occurrence in the pre-COVID and post-COVID era
COVID-19 pandemic is thought to have changed the epidemiology of some pediatric neurosurgical disease: among them are the intracranial complications of sinusitis and otitis (ICSO). According to some studies on...
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Open AccessEarly detection of nerve involvement in presymptomatic TTR mutation carriers: exploring potential markers of disease onset
Hereditary transthyretin (ATTRv) amyloidosis is a heterogeneous, progressive, multisystemic disease with a life-threatening course if left untreated. Given the current availability of effective therapies, clos...
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Open AccessAcute treatment of migraine: quantifying the unmet need through real-world data in Italy
This study is describing subjects with migraine interrupting or not receiving triptans for acute treatment and providing a national-level estimate of people who might benefit from different therapeutic approac...
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Open AccessNon-pharmacological treatment of hereditary spastic paraplegia: a systematic review