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  1. No Access

    Article

    Seizures in autoimmune-associated epilepsy: a long-term video-EEG monitoring study

    Joana Fonte, Andrea Stabile, Marco de Curtis, Roberta Di Giacomo in Journal of Neurology (2024)

  2. Article

    Open Access

    Amyotrophic lateral sclerosis stratification: unveiling patterns with virome, inflammation, and metabolism molecules

    Amyotrophic lateral sclerosis (ALS) is an untreatable and clinically heterogeneous condition primarily affecting motor neurons. The ongoing quest for reliable biomarkers that mirror the disease status and prog...

    Elena Niccolai, Matteo Pedone, Ilaria Martinelli, Giulia Nannini in Journal of Neurology (2024)

  3. No Access

    Article

    The chronic use of serotonin norepinephrine reuptake inhibitors facilitates dyskinesia priming in early Parkinson’s disease

    Parkinson’s disease (PD) patients are frequently exposed to antidepressant medications (ADMs). Norepinephrine (NE) and serotonin (5HT) systems have a role in levodopa-induced dyskinesias (LID) pathophysiology.

    Massimo Marano, Andrea Pilotto, Alessandro Padovani, Deepak Gupta in Journal of Neurology (2024)

  4. Article

    Open Access

    ChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis

    ChatGPT is an open-source natural language processing software that replies to users’ queries. We conducted a cross-sectional study to assess people living with Multiple Sclerosis’ (PwMS) preferences, satisfac...

    Elisabetta Maida, Marcello Moccia, Raffaele Palladino in Journal of Neurology (2024)

  5. No Access

    Article

    History of traumatic brain injury is associated with increased grey-matter loss in patients with mild cognitive impairment

    To investigate whether a history of traumatic brain injury (TBI) is associated with greater long-term grey-matter loss in patients with mild cognitive impairment (MCI).

    Marc A. Khoury, Nathan W. Churchill, Alex Di Battista in Journal of Neurology (2024)

  6. No Access

    Article

    Clinical and genetic characteristics of 1672 cases of amyotrophic lateral sclerosis in China: a single-center retrospective study

    Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. In recent years, continuous discoveries of new ALS-causing genes have enhanced the understanding of the genotype–phenotype relationship...

    Dongchao Shen, Xunzhe Yang, Di He, Kang Zhang, Shuangwu Liu in Journal of Neurology (2024)

  7. Article

    Open Access

    CDKL5 deficiency-related neurodevelopmental disorders: a multi-center cohort study in Italy

    CDKL5 deficiency disorder (CDD) is a complex clinical condition resulting from non-functional or absent CDKL5 protein, a serine–threonine kinase pivotal for neural maturation and synaptogenesis. The disorder m...

    Giovanni Battista Dell’Isola, Fattorusso Antonella in Journal of Neurology (2024)

  8. Article

    Open Access

    Midterm follow-up after embolization of intracranial aneurysms proximal to the circle of Willis with the Silk Vista flow diverter: the I-MAMA registry

    The aim of this registry was to assess technical success, procedural safety and mid- to long-term follow-up results of the Silk Vista “Mama” (SVM) flow diverter (BALT, Montmorency, France) for the treatment of...

    Valerio Da Ros, Federico Sabuzi, Francesco D’Argento in Neuroradiology (2024)

  9. Article

    Open Access

    Sex impacts treatment decisions in multiple sclerosis

    Individual disease-modifying treatment (DMT) decisions might differ between female and male people with MS (pwMS).

    Harald Hegen, Klaus Berek, Florian Deisenhammer, Thomas Berger in Journal of Neurology (2024)

  10. Article

    Open Access

    Early intensive versus escalation treatment in patients with relapsing–remitting multiple sclerosis in Austria

    To compare the effectiveness of early intensive treatment (EIT) versus escalation treatment (ESC) in a nationwide observational cohort of almost 1000 people with relapsing–remitting multiple sclerosis (RRMS).

    Michael Guger, Christian Enzinger, Fritz Leutmezer in Journal of Neurology (2024)

  11. Article

    Open Access

    Progression independent of relapse activity in relapsing multiple sclerosis: impact and relationship with secondary progression

    We investigated the occurrence and relative contribution of relapse-associated worsening (RAW) and progression independent of relapse activity (PIRA) to confirmed disability accrual (CDA) and transition to sec...

    Emilio Portaccio, Matteo Betti, Ermelinda De Meo, Ilaria Addazio in Journal of Neurology (2024)

  12. Article

    Open Access

    Correction to: Ultra-late response (> 24 weeks) to anti-CGRP monoclonal antibodies in migraine: a multicenter, prospective, observational study

    Piero Barbanti, Cinzia Aurilia, Gabriella Egeo, Stefania Proietti in Journal of Neurology (2024)

  13. Article

    Open Access

    The role of ethnicity and native-country income in multiple sclerosis: the Italian multicentre study (MS-MigIT)

    Multiple sclerosis (MS) is a complex disorder in which environmental and genetic factors interact modifying disease risk and course. This multicentre, case–control study involving 18 Italian MS Centres investi...

    Alessia Bianchi, Domenica Matranga, Francesco Patti in Journal of Neurology (2024)

  14. Article

    Open Access

    Ultra-late response (> 24 weeks) to anti-CGRP monoclonal antibodies in migraine: a multicenter, prospective, observational study

    Nearly 60% of migraine patients treated with monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway experience a ≥ 50% reduction in monthly migraine days (MMD) at 12 weeks co...

    Piero Barbanti, Cinzia Aurilia, Gabriella Egeo, Stefania Proietti in Journal of Neurology (2024)

  15. Article

    Open Access

    A Delphi consensus to identify the key screening tests/questions for a digital neurological examination for epidemiological research

    Most neurological diseases have no curative treatment; therefore, focusing on prevention is key. Continuous research to uncover the protective and risk factors associated with different neurological diseases i...

    Vasco Ribeiro Ferreira, Carol Brayne, Paolo Ragonese in Journal of Neurology (2024)

  16. Article

    Open Access

    Altered domain-specific striatal functional connectivity in patients with Parkinson’s disease and urinary symptoms

    In this study, we aimed at investigating the possible association of urinary symptoms with whole-brain MRI resting-state functional connectivity (FC) alterations from distinct striatal subregions in a large co...

    Noemi Piramide, Rosa De Micco, Federica Di Nardo in Journal of Neural Transmission (2024)

  17. No Access

    Article

    Does thyroid diseases contribute to the natural history of idiopathic adult-onset dystonia? Data from the Italian Dystonia Registry

    A few earlier observations and recent controlled studies pointed to the possible contribution of thyroid diseases in idiopathic adult-onset dystonia (IAOD). The aim of this study was to investigate the associa...

    Sarah Idrissi, Vittorio Velucci, Marcello Esposito in Journal of Neural Transmission (2024)

  18. No Access

    Article

    Evaluation of drivers of treatment switch in relapsing multiple sclerosis: a study from the Italian MS Registry

    Active relapsing–remitting (RR) and secondary progressive (SP) multiple sclerosis (MS) are currently defined as “relapsing MS” (RMS). The aim of this cross-sectional study was to assess drivers of treatment sw...

    Pietro Iaffaldano, Giuseppe Lucisano, Tommaso Guerra in Journal of Neurology (2024)

  19. No Access

    Article

    The prognostic value of systematic genetic screening in amyotrophic lateral sclerosis patients

    Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with complex genetic architecture. Emerging evidence has indicated comorbidity between ALS and autoimmune conditions, suggesting a potential s...

    Di He, Yining Liu, Siqi Dong, Dongchao Shen, Xunzhe Yang, Meng Hao in Journal of Neurology (2024)

  20. No Access

    Article

    Multiple sclerosis in the elderly: a retrospective cohort study

    There is a lack of knowledge of disease course, prognosis, comorbidities and potential treatments of elderly MS patients.

    Anne Zinganell, Georg Göbel, Klaus Berek, Barbara Hofer in Journal of Neurology (2024)

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