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443 Result(s)
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Article
Seizures in autoimmune-associated epilepsy: a long-term video-EEG monitoring study
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Article
Open AccessAmyotrophic lateral sclerosis stratification: unveiling patterns with virome, inflammation, and metabolism molecules
Amyotrophic lateral sclerosis (ALS) is an untreatable and clinically heterogeneous condition primarily affecting motor neurons. The ongoing quest for reliable biomarkers that mirror the disease status and prog...
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The chronic use of serotonin norepinephrine reuptake inhibitors facilitates dyskinesia priming in early Parkinson’s disease
Parkinson’s disease (PD) patients are frequently exposed to antidepressant medications (ADMs). Norepinephrine (NE) and serotonin (5HT) systems have a role in levodopa-induced dyskinesias (LID) pathophysiology.
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Open AccessChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis
ChatGPT is an open-source natural language processing software that replies to users’ queries. We conducted a cross-sectional study to assess people living with Multiple Sclerosis’ (PwMS) preferences, satisfac...
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Article
History of traumatic brain injury is associated with increased grey-matter loss in patients with mild cognitive impairment
To investigate whether a history of traumatic brain injury (TBI) is associated with greater long-term grey-matter loss in patients with mild cognitive impairment (MCI).
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Clinical and genetic characteristics of 1672 cases of amyotrophic lateral sclerosis in China: a single-center retrospective study
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. In recent years, continuous discoveries of new ALS-causing genes have enhanced the understanding of the genotype–phenotype relationship...
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Open AccessCDKL5 deficiency-related neurodevelopmental disorders: a multi-center cohort study in Italy
CDKL5 deficiency disorder (CDD) is a complex clinical condition resulting from non-functional or absent CDKL5 protein, a serine–threonine kinase pivotal for neural maturation and synaptogenesis. The disorder m...
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Open AccessMidterm follow-up after embolization of intracranial aneurysms proximal to the circle of Willis with the Silk Vista flow diverter: the I-MAMA registry
The aim of this registry was to assess technical success, procedural safety and mid- to long-term follow-up results of the Silk Vista “Mama” (SVM) flow diverter (BALT, Montmorency, France) for the treatment of...
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Article
Open AccessSex impacts treatment decisions in multiple sclerosis
Individual disease-modifying treatment (DMT) decisions might differ between female and male people with MS (pwMS).
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Article
Open AccessEarly intensive versus escalation treatment in patients with relapsing–remitting multiple sclerosis in Austria
To compare the effectiveness of early intensive treatment (EIT) versus escalation treatment (ESC) in a nationwide observational cohort of almost 1000 people with relapsing–remitting multiple sclerosis (RRMS).
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Article
Open AccessProgression independent of relapse activity in relapsing multiple sclerosis: impact and relationship with secondary progression
We investigated the occurrence and relative contribution of relapse-associated worsening (RAW) and progression independent of relapse activity (PIRA) to confirmed disability accrual (CDA) and transition to sec...
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Open AccessCorrection to: Ultra-late response (> 24 weeks) to anti-CGRP monoclonal antibodies in migraine: a multicenter, prospective, observational study
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Open AccessThe role of ethnicity and native-country income in multiple sclerosis: the Italian multicentre study (MS-MigIT)
Multiple sclerosis (MS) is a complex disorder in which environmental and genetic factors interact modifying disease risk and course. This multicentre, case–control study involving 18 Italian MS Centres investi...
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Open AccessUltra-late response (> 24 weeks) to anti-CGRP monoclonal antibodies in migraine: a multicenter, prospective, observational study
Nearly 60% of migraine patients treated with monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway experience a ≥ 50% reduction in monthly migraine days (MMD) at 12 weeks co...
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Open AccessA Delphi consensus to identify the key screening tests/questions for a digital neurological examination for epidemiological research
Most neurological diseases have no curative treatment; therefore, focusing on prevention is key. Continuous research to uncover the protective and risk factors associated with different neurological diseases i...
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Open AccessAltered domain-specific striatal functional connectivity in patients with Parkinson’s disease and urinary symptoms
In this study, we aimed at investigating the possible association of urinary symptoms with whole-brain MRI resting-state functional connectivity (FC) alterations from distinct striatal subregions in a large co...
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Does thyroid diseases contribute to the natural history of idiopathic adult-onset dystonia? Data from the Italian Dystonia Registry
A few earlier observations and recent controlled studies pointed to the possible contribution of thyroid diseases in idiopathic adult-onset dystonia (IAOD). The aim of this study was to investigate the associa...
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Evaluation of drivers of treatment switch in relapsing multiple sclerosis: a study from the Italian MS Registry
Active relapsing–remitting (RR) and secondary progressive (SP) multiple sclerosis (MS) are currently defined as “relapsing MS” (RMS). The aim of this cross-sectional study was to assess drivers of treatment sw...
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Article
The prognostic value of systematic genetic screening in amyotrophic lateral sclerosis patients
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with complex genetic architecture. Emerging evidence has indicated comorbidity between ALS and autoimmune conditions, suggesting a potential s...
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Multiple sclerosis in the elderly: a retrospective cohort study
There is a lack of knowledge of disease course, prognosis, comorbidities and potential treatments of elderly MS patients.