4,940 Result(s)
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Open AccessImaging-based body fat distribution and diabetic retinopathy in general US population with diabetes: an NHANES analysis (2003–2006 and 2011–2018)
Limited studies have investigated the correlation between fat distribution and the risk of diabetic retinopathy (DR) in the general population with diabetes. The relationship between obesity and DR remains inc...
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Open AccessEfficacy and safety of glucocorticoids in the treatment of COVID-19: a systematic review and meta-analysis of RCTs
In the realm of acute respiratory infections, coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a global public health challenge. The application ...
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Open AccessLncRNA PITPNA-AS1 mediates the diagnostic potential of miR-129-5p in prostate cancer
LncRNA has an effective value in many diseases, which has long been applied in the diagnosis, treatment and prognosis of prostate cancer. This study focused on lncRNA PITPNA-AS1, and its diagnostic potential i...
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Open AccessEffect of spin-lock frequency on quantitative myocardial T1ρ map**
To use T1ρ map** to assess myocardial fibrosis and to provide a reference for future clinical application, it is necessary to understand the factors influencing T1ρ values. This study explored the influence ...
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Open AccessPreliminarily exploring the intraoperative ultrasonography characteristics of patients with degenerative cervical myelopathy
How to quickly read and interpret intraoperative ultrasound (IOUS) images of patients with degenerative cervical myelopathy (DCM) to obtain meaningful information? Few studies have systematically explored this...
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Open AccessSelf-assembled nanoparticles of costunolide and glycyrrhizic acid for enhanced ulcerative colitis treatment
Ulcerative colitis (UC) is a persistent inflammatory condition that specifically targets the colon and rectum. Existing therapies fail to adequately address the clinical requirements of people suffering from t...
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Open AccessAn adult with hemorrhagic varicella co-infects with cytomegalovirus: a case report
Hemorrhagic varicella (HV) is a particular form of chicken pox.,with high mortality in adults. This form of the disease is rare, to date, approximately 4 cases have been reported. Occasional cases of HV have b...
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Open AccessIntegrated network pharmacology and metabolomics to reveal the mechanism of Pinellia ternata inhibiting non-small cell lung cancer cells
Lung cancer is a malignant tumor with highly heterogeneous characteristics. A classic Chinese medicine, Pinellia ternata (PT), was shown to exert therapeutic effects on lung cancer cells. However, its chemical an...
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Open AccessAssociation between different obesity patterns and the risk of NAFLD detected by transient elastography: a cross-sectional study
Obesity has become a major global public health challenge. Studies examining the associations between different obesity patterns and the risk of nonalcoholic fatty liver disease (NAFLD) are limited. This study...
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Open AccessNormalized lactate load as an independent prognostic indicator in patients with cardiogenic shock
Early prognosis evaluation is crucial for decision-making in cardiogenic shock (CS) patients. Dynamic lactate assessment, for example, normalized lactate load, has been a better prognosis predictor than single...
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Open AccessDeep learning in pulmonary nodule detection and segmentation: a systematic review
The accurate detection and precise segmentation of lung nodules on computed tomography are key prerequisites for early diagnosis and appropriate treatment of lung cancer. This study was designed to compare det...
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Open AccessAuthor Correction: Reducing short-acting beta-agonist use in asthma: Impact of national incentives on prescribing practices in England and the findings from SENTINEL Plus early adopter sites
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Open AccessInvestigation of prognostic values of immune infiltration and LGMN expression in the microenvironment of osteosarcoma
Osteosarcoma (OS), the most common primary malignant bone tumor, predominantly affects children and young adults and is characterized by high invasiveness and poor prognosis. Despite therapeutic advancements, ...
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Open AccessA model for identifying potentially inappropriate medication used in older people with dementia: a machine learning study
Older adults with dementia often face the risk of potentially inappropriate medication (PIM) use. The quality of PIM evaluation is hindered by researchers' unfamiliarity with evaluation criteria for inappropri...
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Open AccessMachine learning models to predict systemic inflammatory response syndrome after percutaneous nephrolithotomy
The objective of this study was to develop and evaluate the performance of machine learning models for predicting the possibility of systemic inflammatory response syndrome (SIRS) following percutaneous nephro...
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Open AccessThe role of anti-citrullinated protein antibody in pathogenesis of RA
Rheumatoid arthritis (RA) is a common autoimmune rheumatic disease that causes chronic synovitis, bone erosion, and joint destruction. The autoantigens in RA include a wide array of posttranslational modified ...
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Open AccessEffects of the subtypes of apolipoprotein E on immune inhibition and prognosis in patients with Hepatocellular Carcinoma
To investigate whether prognosis of patients with hepatocellular carcinoma (HCC) is affected by the abundance and subgroups of myeloid-derived suppressor cells (MDSCs) as well as subtypes and expression of apo...
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Open AccessA deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori
Helicobacter pylori (H. pylori) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high prevalence and resistance make it difficult to tackle. A graph neur...
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Open AccessA cellular senescence-related signature for predicting prognosis, immunotherapy response, and candidate drugs in patients treated with transarterial chemoembolization (TACE)
Cellular senescence is essential to TME development, progression, and remodeling. Few studies have examined cellular senescence in HCC after TACE. Investigating the relationship between cellular senescence, po...
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Open AccessAnalyzing the correlation between low proportion of hobnail features in papillary thyroid carcinoma and clinical aggressiveness risk
Hobnail features may enhance the clinical aggressiveness of papillary thyroid carcinoma (PTC). However, whether a low proportion (<30%) of these features contributes to increased PTC aggressiveness remains unc...
