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Article
Open AccessA peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosisvirulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response
Tuberculosis (TB) is one of the most prevalent infectious diseases affecting millions worldwide. The currently available anti-TB drugs and vaccines have proved insufficient to contain this scourge, necessitati...
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Article
Open AccessHigh glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro
Maternal diabetes alters the global epigenetic mechanisms and expression of genes involved in neural tube development in mouse embryos. Since DNA methylation is a critical epigenetic mechanism that regulates g...
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Article
Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
Non-human primate models will expedite therapeutics and vaccines for coronavirus disease 2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
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Article
Author Correction: Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
A Correction to this paper has been published: https://doi.org/10.1038/s41564-021-00867-2.
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Article
Open AccessGeochemical variations due to salinization in groundwater along the southeast coast of India
In recent years, the extraction of groundwater (GW) in coastal aquifers has rendered the fragile aquifers more saline due to the sea water intrusion. Groundwater from the coastal aquifers of the Pudhucherry re...
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Article
Open AccessDiagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples
Sensitive and specific blood-based assays for the detection of pulmonary and extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses, particularly in children. Here we report a nano...
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Article
Open AccessMonitoring of spatio-temporal glaciers dynamics in Bhagirathi Basin, Gharhwal Himalayas using remote sensing data
Glacier retreat represents a highly sensitive indicator of climate change and global warming. Therefore, timely map** and monitoring of glacier dynamics is strategic for water budget forecasting and sustaina...
