4 Result(s)
within
Denise M. Scholtens
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessVariants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
The duration of pregnancy is influenced by fetal and maternal genetic and non-genetic factors. Here we report a fetal genome-wide association meta-analysis of gestational duration, and early preterm, preterm, ...
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Article
Open AccessMethylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers
Mutations in isocitrate dehydrogenases 1 and 2 (IDHmut) are present in a variety of cancers, including glioma, acute myeloid leukemia (AML), melanoma, and cholangiocarcinoma. These mutations promote hypermethylat...
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Article
Genome-wide associations for birth weight and correlations with adult disease
Multi-ancestry genome-wide association analyses for birth weight in 153,781 individuals identified 60 genomic loci in which birth weight and fetal genotype were associated and found an inverse genetic correlat...
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Article
Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1
Maternal glucose levels during pregnancy impact the develo** fetus, affecting metabolic health both early and later on in life. Both genetic and environmental factors influence maternal metabolism, but littl...
