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  1. Article

    Open Access

    HELLO: improved neural network architectures and methodologies for small variant calling

    Modern Next Generation- and Third Generation- Sequencing methods such as Illumina and PacBio Circular Consensus Sequencing platforms provide accurate sequencing data. Parallel developments in Deep Learning hav...

    Anand Ramachandran, Steven S. Lumetta, Eric W. Klee, Deming Chen in BMC Bioinformatics (2021)

  2. Article

    Open Access

    TIGER: tiled iterative genome assembler

    With the cost reduction of the next-generation sequencing (NGS) technologies, genomics has provided us with an unprecedented opportunity to understand fundamental questions in biology and elucidate human disea...

    **ao-Long Wu, Yun Heo, Izzat El Hajj, Wen-Mei Hwu, Deming Chen in BMC Bioinformatics (2012)