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Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer

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  1. Article

    Open Access

    Alternative dosing regimen of exemestane in a randomized presurgical trial: the role of obesity in biomarker modulation

    In a 3-arm presurgical trial, four-six weeks exemestane 25 mg three times/week (TIW) was non-inferior to 25 mg/day (QD) in suppressing circulating estradiol in postmenopausal women with ER-positive breast canc...

    Harriet Johansson, Aliana Guerrieri-Gonzaga, Sara Gandini… in npj Breast Cancer (2024)

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  2. Article

    Open Access

    Association of CYP2D6 genotype and tamoxifen metabolites with breast cancer recurrence in a low-dose trial

    Low-dose tamoxifen halves recurrence in non-invasive breast cancer without significant adverse events. Some adjuvant trials with tamoxifen 20 mg/day had shown an association between low endoxifen levels (9–16 ...

    Andrea DeCensi, Harriet Johansson, Thomas Helland, Matteo Puntoni… in npj Breast Cancer (2021)

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