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  1. No Access

    Article

    The role of LAT1 in 18F-DOPA uptake in malignant gliomas

    Positron emission tomography (PET) imaging with the amino acid tracer 6-18F-fluoro-l-3,4-dihydroxy-phenylalanine (18F-DOPA) may provide better spatial and functional information in human gliomas than CT or MRI al...

    Ryan S. Youland, Gaspar J. Kitange, Timothy E. Peterson… in Journal of Neuro-Oncology (2013)

  2. No Access

    Article

    Evaluation of RANO response criteria compared to clinician evaluation in WHO grade III anaplastic astrocytoma: implications for clinical trial reporting and patterns of failure

    The utility of current response criteria has not been established in anaplastic astrocytoma (AA). We retrospectively reviewed MR images for 20 patients with AA and compared RANO-based approaches to clinician i...

    Tomas Kazda, John G. Hardie, Deanna H. Pafundi… in Journal of Neuro-Oncology (2015)

  3. No Access

    Article

    Prospective trial evaluating the sensitivity and specificity of 3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine (18F-DOPA) PET and MRI in patients with recurrent gliomas

    Treatment-related changes can be difficult to differentiate from progressive glioma using MRI with contrast (CE). The purpose of this study is to compare the sensitivity and specificity of 18F-DOPA-PET and MRI...

    Ryan S. Youland, Deanna H. Pafundi, Debra H. Brinkmann… in Journal of Neuro-Oncology (2018)

  4. No Access

    Article

    Initial results of a phase II trial of 18F-DOPA PET-guided re-irradiation for recurrent high-grade glioma

    In-field high-grade glioma (HGG) recurrence is a common challenge with limited treatment options, including re-irradiation. The radiotracer 3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine (18F-DOPA) crosses the bloo...

    William G. Breen, Ryan S. Youland, Sharmila Giri… in Journal of Neuro-Oncology (2022)