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Article
A metabolic map and artificial intelligence-aided identification of nasopharyngeal carcinoma via a single-cell Raman platform
Nasopharyngeal carcinoma (NPC) is a complex cancer influenced by various factors. This study explores the use of single-cell Raman spectroscopy as a potential diagnostic tool for investigating biomolecular cha...
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Article
Open AccessdbCNV: deleteriousness-based model to predict pathogenicity of copy number variations
Copy number variation (CNV) is a type of structural variation, which is a gain or loss event with abnormal changes in copy number. Methods to predict the pathogenicity of CNVs are required to realize the relat...
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Article
Open AccessComparison of single cell sequencing data between two whole genome amplification methods on two sequencing platforms
Research based on a strategy of single-cell low-coverage whole genome sequencing (SLWGS) has enabled better reproducibility and accuracy for detection of copy number variations (CNVs). The whole genome amplifi...
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Article
Profiling of downregulated blood-circulating miR-150-5p as a novel tumor marker for cholangiocarcinoma
Altered microRNA (miRNA) expression plays a role in cholangiocarcinoma (CCA) development; thus, detection of blood-circulating miRNAs could be useful as CCA markers. This study profiled serum miRNA levels in p...
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Article
Co-expression of COX-2 and 5-LO in primary glioblastoma is associated with poor prognosis
Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) are important factors in tumorigenesis and malignant progression; however, studies of their roles in glioblastoma have produced conflicting results. To defin...
