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  1. Article

    Open Access

    iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells

    Doxorubicin is one of the few chemotherapeutic drugs able to exert both cytotoxic and pro-immunogenic effects against cancer cells. Following the drug administration, the intracellular protein calreticulin is ...

    Sara De Boo, Joanna Kopecka, Davide Brusa, Elena Gazzano, Lina Matera in Molecular Cancer (2009)

  2. Article

    Open Access

    Correlation between NK function and response to trastuzumab in metastatic breast cancer patients

    Trastuzumab is a monoclonal antibody selectively directed against Her2 and approved for the treatment of Her2 overexpressing breast cancer patients. Its proposed mechanisms of action include mediation of antib...

    Alessandra Beano, Elena Signorino, Andrea Evangelista in Journal of Translational Medicine (2008)