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Article
Open AccessiNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells
Doxorubicin is one of the few chemotherapeutic drugs able to exert both cytotoxic and pro-immunogenic effects against cancer cells. Following the drug administration, the intracellular protein calreticulin is ...
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Article
Open AccessCorrelation between NK function and response to trastuzumab in metastatic breast cancer patients
Trastuzumab is a monoclonal antibody selectively directed against Her2 and approved for the treatment of Her2 overexpressing breast cancer patients. Its proposed mechanisms of action include mediation of antib...