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  1. Article

    Open Access

    Case report: recurrent metastatic breast cancer in internal mammary dissection bed discovered at the time of coronary bypass

    Many patients who undergo coronary artery bypass surgery have a prior history of cancer and potentially chest radiation which is a known risk factor for coronary atherosclerosis. Prior radiation increases fibr...

    Gavitt A. Woodard, Hannah Lee… in Journal of Cardiothoracic Surgery (2019)

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    Chapter

    Lung Cancer Staging and Prognosis

    The seventh edition of the non-small cell lung cancer (NSCLC) TNM staging system was developed by the International Association for the Staging of Lung Cancer (IASLC) Lung Cancer Staging Project by a coordinat...

    Gavitt A. Woodard, Kirk D. Jones, David M. Jablons in Lung Cancer (2016)

  3. No Access

    Article

    Measurement of genome-wide DNA methylation predicts survival benefits from chemotherapy in non-small cell lung cancer

    Novel molecular predictive biomarkers for chemotherapy have been screened and validated in non-small cell lung cancer (NSCLC). However, there was no report on the correlation of genome-wide DNA methylation wit...

    Min-Li Mo, Jie Ma, Zhao Chen, Bing Wei… in Journal of Cancer Research and Clinical On… (2015)

  4. No Access

    Article

    The role of cancer stem cells in neoplasia of the lung: past, present and future

    Through the identification and subsequent targeting of an exquisitely unique and phenotypically defined cancer stem-cell population exhibiting discrete therapeutic vulnerabilities (a potential source of tumor ...

    Adam Yagui-Beltrán, Biao He, David M. Jablons in Clinical and Translational Oncology (2008)

  5. No Access

    Article

    Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis

    The Wnt family of secreted glycoproteins is widely involved in cell proliferation, differentiation and oncogenesis. Many Wnt signaling genes are upregulated and activated in chronic lymphocytic leukemia. Less ...

    Julien Mazieres, Liang You, Biao He, Zhidong Xu, Amie Y Lee, Iwao Mikami… in Oncogene (2005)

  6. No Access

    Article

    Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations

    Aberrant Wnt signaling, mainly through mutations of APC and in some cases of CTNNB1 or AXIN2, has been found in the majority of colorectal cancers. Recently, frequent promoter hypermethylation was identified to c...

    Biao He, Noemi Reguart, Liang You, Julien Mazieres, Zhidong Xu, Amie Y Lee… in Oncogene (2005)

  7. No Access

    Article

    Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma

    Secreted frizzled-related proteins (sFRPs) comprise a family of five secreted glycoproteins that antagonize Wnt signaling. Aberrant activation and upregulation of the Wnt pathway is a key feature of many cance...

    Amie Y Lee, Biao He, Liang You, Sina Dadfarmay, Zhidong Xu, Julien Mazieres… in Oncogene (2004)

  8. No Access

    Article

    Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells

    In this report, we have demonstrated that Wnt-2 protein is overexpressed in freshly resected human non-small-cell lung cancer (NSCLC) tissues. We have also developed a monoclonal antibody against the N-terminu...

    Liang You, Biao He, Zhidong Xu, Kazutsugu Uematsu, Julien Mazieres, Iwao Mikami… in Oncogene (2004)

  9. No Access

    Protocol

    Matrix Metalloproteinase Expression in Lung Cancer

    The importance of matrix metalloproteinases (MMPs) in the growth and spread of solid tumors has been known for over a decade (1,2). However, the molecular mechanisms that regulate their expression and the elucida...

    Melissa Lim, David M. Jablons in Lung Cancer (2003)