9 Result(s)
within
David Kaplan
Inorganic Chemistry
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Article
Morphology and Crystallinity Control of Novel Spider Silk-like Block Copolymer
A new family of A-B di-block copolymers based on the amino acid sequences of Nephila clavipes major ampulate dragline spider silk, which have a strong potential for applications in tissue regeneration and drug de...
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Article
Young’s Modulus of Cortical and P19 Derived Neurons Measured by Atomic Force Microscopy
In this paper we use the Atomic Force Microscope to measure the Young’s modulus for two types of neuronal cell bodies: cortical neurons obtained from rat embryos and neurons derived from P19 mouse embryonic ca...
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Article
Thermal analysis of spider silk inspired di-block copolymers in the glass transition region by TMDSC
We used advanced thermal analysis methods to characterize a new family of A-B di-block copolymers based on the amino acid sequences of Nephila clavipes major ampulate dragline spider silk. Using temperature modul...
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Article
Surface Enhanced Vibrational Spectroscopy of Proteins with Plasmonic Nanoantenna Arrays
Infrared absorption spectroscopy is a powerful tool for structural and functional studies of biomolecules. The technique enables direct access to the vibrational fingerprints of molecular bonds in the mid-infr...
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Article
Thermal analysis of protein–metallic ion systems
Advanced thermal analysis methods, such as temperature modulated DSC (differential scanning calorimetry) and quasi-isothermal TMDSC were used to analyze the protein–metallic ion interactions in silk fibroin pr...
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Article
Interfacing Conducting Polymers and Biological Macromolecules: A Case Study of Insecticide Biosensor Development
The creation of smart materials is a current goal of many laboratories including our own. We are involved in studying a number of thin film and monolayer systems which share the common features of involving hi...
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Article
Molecular Order in Silk Secretions
Transmitted polarized light microscopy of various natural silk secretions reveals their ability to form nematic liquid crystalline phases. Observations of microstructure, together with a simple secondary struc...
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Chapter
The Biosynthesis of Unusual Polyamides Containing Glutamic Acid
A study of the effect of culture time and the availability of nutrients on the production and molecular weight of bacterially derived γ-polyglutamic acid (γ-PGA) has been carried out. The introduction of addit...
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Article
Liquid Crystalline Characteristics of Natural Silk Secretions
We have used transmitted polarized light microscopy to examine the fluid contents of silk glands taken from Bombyx mori silkworms and Nephila clavipes orb-weaving spiders. In the absence of shear, the secretions ...
