3 Result(s)
within
David Cheillan
Life Sciences
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Protocol
Amino Acid Profiling for the Diagnosis of Inborn Errors of Metabolism
The diagnosis of inherited metabolic disorders of amino acid (AA) metabolism is based on the qualitative and/or the quantitative analysis of AAs, mainly in blood and urine. For years, the most widespread techn...
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Article
Open AccessTNF-α- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism
Muscle atrophy associated with various pathophysiological conditions represents a major health problem, because of its contribution to the deterioration of patient status and its effect on mortality. Although ...
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Article
Open AccessSphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells
Elevated levels of the pro-inflammatory cytokine tumor necrosis factor-α (TNFα) inhibit erythropoiesis and cause anemia in patients with cancer and chronic inflammatory diseases. TNFα is also a potent activato...
