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    Article

    Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial

    The STEP HIV-1 vaccine trial failed to protect volunteers from infection, but whether vaccine-driven immune responses affected the profile of viral variants in infected individuals was unknown. By analyzing nu...

    Morgane Rolland, Sodsai Tovanabutra, Allan C deCamp, Nicole Frahm in Nature Medicine (2011)

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    Open Access

    In vitro activity of dolutegravir against wild-type and integrase inhibitor-resistant HIV-2

    Dolutegravir recently became the third integrase strand transfer inhibitor (INSTI) approved for use in HIV-1–infected individuals. In contrast to the extensive dataset for HIV-1, in vitro studies and clinical ...

    Robert A Smith, Dana N Raugi, Charlotte Pan, Papa Salif Sow, Moussa Seydi in Retrovirology (2015)