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Article
The secondary visual cortex mediated the enhancement of associative learning on methamphetamine self-administration behaviors
Methamphetamine addiction is a persistent and intractable pathological learning and memory, whereas no approved therapeutics is available. However, few attentions have been paid to how associative learning par...
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Article
Dorsolateral striatal miR-134 modulates excessive methamphetamine intake in self-administering rats
Increasing evidence indicates that excessive drug consumption is sufficient for the transition from recreational and controlled drug use to uncontrolled use and addiction. However, the underlying mechanisms ar...
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Article
Modulation of miR-139-5p on chronic morphine-induced, naloxone-precipitated cAMP overshoot in vitro
Chronic exposure to morphine can produce tolerance, dependence and addiction, but the underlying neurobiological basis is still incompletely understood. c-Jun, as an important component of the activator protei...
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Article
Antidepressant-like action of agmatine in the acute and sub-acute mouse models of depression: a receptor mechanism study
Previous studies have shown that agmatine, a potential neuromodulator or co-transmitter, exhibited antidepressant-like action in animal models, yet its mechanism, especially the receptor mechanism, remains unc...
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Article
Nucleus accumbens hyperpolarization-activated cyclic nucleotide-gated channels modulate methamphetamine self-administration in rats
Methamphetamine addiction is believed to primarily result from increased dopamine release and the inhibition of dopamine uptake. Some evidence suggests that hyperpolarization-activated cyclic nucleotide-gated ...