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Real-world study of a novel prognostic scoring system: for a more precise prognostication and better clinical treatment guidance in stages II and III colon cancer

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  1. Article

    Open Access

    Circulating basophil count as a prognostic marker of tumor aggressiveness and survival outcomes in colorectal cancer

    Accumulating evidence demonstrated immune/inflammation-related implications of basophils in affecting tissue microenvironment that surrounded a tumor, and this study aimed to elucidate the clinical value of se...

    Qi Liu, Dakui Luo, Sanjun Cai, Qingguo Li in Clinical and Translational Medicine (2020)

  2. Article

    Open Access

    Long noncoding RNA TRPM2-AS acts as a microRNA sponge of miR-612 to promote gastric cancer progression and radioresistance

    Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis and are frequently dysregulated in cancers. Here, we identify a critical lncRNA TRPM2-AS which is aberrantly expressed in gas...

    Jian **ao, Linling Lin, Dakui Luo, Liang Shi, Wangwang Chen, Hao Fan in Oncogenesis (2020)

  3. Article

    Open Access

    CUL4B-DDB1-COP1-mediated UTX downregulation promotes colorectal cancer progression

    UTX (encoded by KDM6A), a histone demethylase for H3K27me2/3, is frequently mutated in human cancers. However, its functional and regulatory mechanisms in colorectal cancer (CRC) remain unclear.

    Dakui Luo, Min Chen, Qingguo Li, Kangjunjie Wang in Experimental Hematology & Oncology (2023)

  4. Article

    Open Access

    Conditional survival and the prognostic value of serum carcinoembryonic antigen level in oldest old with colorectal cancer

    To evaluate the clinical value of serum CEA levels and their implications on the diagnostic value of the conventional TNM staging system in the oldest-old patients with colorectal cancer (CRC).

    Wei**g He, Yufei Yang, Qi Liu, Dakui Luo, Qingguo Li, **nxiang Li in BMC Gastroenterology (2024)