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  1. Article

    Open Access

    CUL4B-DDB1-COP1-mediated UTX downregulation promotes colorectal cancer progression

    UTX (encoded by KDM6A), a histone demethylase for H3K27me2/3, is frequently mutated in human cancers. However, its functional and regulatory mechanisms in colorectal cancer (CRC) remain unclear.

    Dakui Luo, Min Chen, Qingguo Li, Kangjunjie Wang in Experimental Hematology & Oncology (2023)