9 Result(s)
within
DaeWon Lee
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessAutomated eyeball volume measurement based on CT images using neural network-based segmentation and simple estimation
With the increase in the dependency on digital devices, the incidence of myopia, a precursor of various ocular diseases, has risen significantly. Because myopia and eyeball volume are related, myopia progressi...
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Article
Open AccessDrosophila immune cells transport oxygen through PPO2 protein phase transition
Insect respiration has long been thought to be solely dependent on an elaborate tracheal system without assistance from the circulatory system or immune cells1,2. Here we describe that Drosophila crystal cells—my...
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Article
Open AccessAtomically synergistic Zn-Cr catalyst for iso-stoichiometric co-conversion of ethane and CO2 to ethylene and CO
Develo** atomically synergistic bifunctional catalysts relies on the creation of colocalized active atoms to facilitate distinct elementary steps in catalytic cycles. Herein, we show that the atomically-syne...
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Article
Open AccessDiabetic sensory neuropathy and insulin resistance are induced by loss of UCHL1 in Drosophila
Diabetic sensory neuropathy (DSN) is one of the most common complications of type 2 diabetes (T2D), however the molecular mechanistic association between T2D and DSN remains elusive. Here we identify ubiquitin...
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Article
Fluidic self-assembly for MicroLED displays by controlled viscosity
Displays in which arrays of microscopic ‘particles’, or chiplets, of inorganic light-emitting diodes (LEDs) constitute the pixels, termed MicroLED displays, have received considerable attention1,2 because they ca...
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Article
Open AccessSingle-cell transcriptome maps of myeloid blood cell lineages in Drosophila
The Drosophila lymph gland, the larval hematopoietic organ comprised of prohemocytes and mature hemocytes, has been a valuable model for understanding mechanisms underlying hematopoiesis and immunity. Three types...
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Article
Open AccessSignal flow control of complex signaling networks
Complex disease such as cancer is often caused by genetic mutations that eventually alter the signal flow in the intra-cellular signaling network and result in different cell fate. Therefore, it is crucial to ...
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Article
Open AccessTopological estimation of signal flow in complex signaling networks
In a cell, any information about extra- or intra-cellular changes is transferred and processed through a signaling network and dysregulation of signal flow often leads to disease such as cancer. So, understand...
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Article
Open AccessA design principle underlying the paradoxical roles of E3 ubiquitin ligases
E3 ubiquitin ligases are important cellular components that determine the specificity of proteolysis in the ubiquitin-proteasome system. However, an increasing number of studies have indicated that E3 ubiquiti...
