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    Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus

    Membrane protein efflux pumps confer antibiotic resistance by extruding structurally distinct compounds and lowering their intracellular concentration. Yet, there are no clinically approved drugs to inhibit ef...

    Douglas N. Brawley, David B. Sauer, Jian** Li, Xuhui Zheng… in Nature Chemical Biology (2022)