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  1. Article

    Open Access

    Ke Hsin Kuo: A distinguished scientist and great mentor

    Da-Neng Wang, Lu-Chang Qin in Protein & Cell (2019)

  2. No Access

    Article

    ATP binding drives substrate capture in an ECF transporter by a release-and-catch mechanism

    Bacterial energy-coupling factor (ECF) transporters mediate ATP-dependent uptake of essential environmental micronutrients. Biochemical and fluorescence analyses now show that ATP binding promotes release of a...

    Nathan K Karpowich, ** Mei Song, Nicolette Cocco in Nature Structural & Molecular Biology (2015)

  3. No Access

    Article

    The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins

    The New York Consortium on Membrane Protein Structure (NYCOMPS) was formed to accelerate the acquisition of structural information on membrane proteins by applying a structural genomics approach. NYCOMPS compr...

    James Love, Filippo Mancia, Lawrence Shapiro in Journal of Structural and Functional Genom… (2010)

  4. No Access

    Article

    Structure and mechanism of a pentameric formate channel

    The structure of the formate channel FocA from Vibrio cholerae reveals a pentamer, with each monomer possessing its own substrate translocation pore. The selectivity filter consists of a central constriction ring...

    Andrew B Waight, James Love, Da-Neng Wang in Nature Structural & Molecular Biology (2010)

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    Article

    Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures

    Sertraline (Zoloft) and fluoxetine (Prozac) are selective serotonin-reuptake inhibitors (SSRIs) that are widely prescribed to treat depression. They bind to the presynaptic plasma membrane serotonin transporte...

    Zheng Zhou, Juan Zhen, Nathan K Karpowich in Nature Structural & Molecular Biology (2009)

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    Protocol

    Purification and Characterization of Transporter Proteins from Human Erythrocyte Membrane

    Functions and biochemical properties of several membrane transporter proteins from human erythrocyte, in particular, the glucose transporter (Glut1) and anion exchanger (AE1, also called Band 3) have been exte...

    Da-Neng Wang, M. Joanne Lemieux, Jonathan M. Boulter in Membrane Protein Protocols (2003)