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  1. No Access

    Article

    H2O2 Induces Myocardial Hypertrophy in H9c2 Cells: A Potential Role of Ube3a

    Myocardial hypertrophy that often leads to eventual heart failure is a leading cause of mortality worldwide. While both apoptosis and cell proliferation have been reported to play an important part in heart fa...

    Rui Song, Jie Zhang, Lijuan Zhang, Guanghua Wang, Da Wo… in Cardiovascular Toxicology (2015)

  2. No Access

    Article

    LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis

    How Wnt signalling including canonical and non-canonical pathways are initiated at the cell surface is not completely understood. Here we report that Wnt receptor Frizzled (Frz) and theco-receptors LRP5 and LR...

    Dan-ni Ren, **xiao Chen, Zhi Li, Hongwei Yan, Yan Yin, Da Wo… in Nature Communications (2015)

  3. Article

    Open Access

    Effects of midwife-led maternity services on postpartum wellbeing and clinical outcomes in primiparous women under China’s one-child policy

    The Midwife-led maternity services have been implemented in China in response to the high rates of primiparous women and Caesarean Sections (CS) which may be related to China’s one-child policy. However, few s...

    **g Hua, Li** Zhu, Li Du, Yu Li, Zhuochun Wu, Da Wo… in BMC Pregnancy and Childbirth (2018)

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  4. Article

    Open Access

    Deletion of low-density lipoprotein-related receptor 5 inhibits liver Cancer cell proliferation via destabilizing Nucleoporin 37

    LRP5/6 are co-receptors in Wnt/β-catenin pathway. Recently, we discovered multiple β-catenin independent functions of LRP5/6 in tumor cells and in the diseased heart. Nucleoporin 37 (NUP37) is an important com...

    **xiao Chen, Da Wo, En Ma, Hongwei Yan, Jun Peng… in Cell Communication and Signaling (2019)

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