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    Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells

    The immune system is central in the pathogenesis of scrapie and other transmissible spongiform encephalopathies (TSEs) or 'prion' diseases1. After infecting by peripheral (intraperitoneal or oral) routes, most TS...

    K.L. Brown, K. Stewart, D.L. Ritchie, N.A. Mabbott, A. Williams in Nature Medicine (1999)