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Article
Regulation of transcription factor E2F3a and its clinical relevance in ovarian cancer
Recently we showed an integral epidermal growth factor receptor (EGFR)–E2F3a signaling path, in which E2F3a was found to be essential in EGFR-mediated proliferation in ovarian cancer cells. The present work ev...
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Article
Alternative splicing of p53 and p73: the novel p53 splice variant p53δ is an independent prognostic marker in ovarian cancer
Similar to p73, the tumor suppressor gene p53 is subject to alternative splicing. Besides p53ΔE6 and p53β, we identified p53ζ, p53δ and p53ɛ, arising from alternative splicing of exon 6 and intron 9, respectively...
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Article
Latest progress in treatment of gynaecological cancers
The present report gives the scope of relevant contributions focusing on the treatment of gynaecologic malignancies presented at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO) held...
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Article
Primary chemotherapy and maintenance therapy in epithelial ovarian cancer
PURPOSE. This overview summarizes the most prominent data on the evolution of first-line and maintenance chemotherapy in epithelial ovarian cancer. METHODS. The literature published on first-line and maintenan...