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  1. Article

    Correction: A new mechanism for induced vitamin D deficiency in calcium deprivation

    A new mechanism for induced vitamin D deficiency in calcium deprivation

    M. R. Clements, L. Johnson, D. R. Fraser in Nature (1990)

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    A new mechanism for induced vitamin D deficiency in calcium deprivation

    Synthesis of vitamin D in the skin in response to ultraviolet light is the main determinant of vitamin D status in man1 and it is therefore surprising that rickets and osteomalacia, clinical signs of vitamin D de...

    M. R. Clements, L. Johnson, D. R. Fraser in Nature (1987)

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    Article

    A vitamin D encyclopaedia

    Vitamin D. The Calcium Homeostatic Steroid Hormone.

    D.R. Fraser in Nature (1980)

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    Article

    Identification of 1,25-Dihydroxycholecalciferol, a New Kidney Hormone controlling Calcium Metabolism

    A vitamin D metabolite, 25-dihydroxycholecalciferol, is further hydroxylated by kidney before acting as a hormone on target tissues. The structure of this kidney metabolite is now described.

    D. E. M. LAWSON, D. R. FRASER, E. KODICEK, H. R. MORRIS, DUDLEY H. WILLIAMS in Nature (1971)

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    Article

    Unique Biosynthesis by Kidney of a Biologically Active Vitamin D Metabolite

    BEFORE the molecule of vitamin D acts in the control of calcium metabolism it is converted to a functional form in at least two metabolic steps. The first, a side chain hydroxylation at carbon 25, was shown by...

    D. R. FRASER, E. KODICEK in Nature (1970)

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    Article

    Conformational Similarities of Vitamin D and Cholesterol as Enzyme Substrates

    INVESTIGATIONS of the synthesis of vitamin D long chain fatty acid esters found in rats have indicated that cholesterol-specific esterifying enzymes in the small intestine and plasma have vitamin D as substrate1....

    D. R. FRASER, E. KODICEK in Nature (1968)