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  1. Article

    Contribution of glucose/glucose 6-phosphate cycle activity to insulin resistance in Type 2 (non-insulin-dependent) diabetes mellitus

    It has been suggested that increased glucose/glucose 6-phosphate substrate cycling impairs net hepatic glucose uptake in Type 2 (non-insulin-dependent) diabetes mellitus and contributes to hyperglycaemia. To i...

    D. P. Rooney, R. D. G. Neely, O. Beatty, N. P. Bell, B. Sheridan in Diabetologia (1993)

  2. Article

    Underestimation of glucose turnover determined using [6-3H]glucose tracer in non-steady state

    The use of tritiated glucose tracers may result in underestimation of glucose turnover during hyperinsulinaemic clamps giving paradoxical negative endogenous glucose production rates. While mathematical modell...

    R. D. G. Neely, D. P. Rooney, A. B. Atkinson, B. Sheridan, C. N. Ennis in Diabetologia (1990)