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866 Result(s)
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Article
Open AccessCorrection: Unveiling the invisible: receivers use object weight cues for grip force planning in handover actions
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Article
Risk calculators for the detection of prostate cancer: a systematic review
Prostate cancer (PCa) (early) detection poses significant challenges, including unnecessary testing and the risk of potential overdiagnosis. The European Association of Urology therefore suggests an individual...
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Open AccessRetinoic acid related orphan receptor α is a genetic modifier that rescues retinal degeneration in a mouse model of Stargardt disease and Dry AMD
Degeneration of the macula is associated with several overlap** diseases including age-related macular degeneration (AMD) and Stargardt Disease (STGD). Mutations in ATP Binding Cassette Subfamily A Member 4 (AB...
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Article
Open AccessUnveiling the invisible: receivers use object weight cues for grip force planning in handover actions
Handover actions are part of our daily lives. Whether it is the milk carton at the breakfast table or tickets at the box office, we usually perform these joint actions without much conscious attention. The ind...
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An Investigation of Clock Gene Variations in Turkish Nannospalax Species
Blind mole rats (Nannospalax) have become famous for their long lifespans and cancer resistance, but it is still unknown what causes them to be resistant to cancer. These animals may have a different melatonin sy...
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Open AccessA MYC-rearrangement is a negative prognostic factor in stage II, but not in stage I diffuse large B-cell lymphoma
MYC oncogene rearrangements (MYC-R) negatively affect survival in patients with Ann Arbor stage III–IV diffuse large B-cell lymphoma (DLBCL), but their impact in limited stage (LS) I–II is unclear. Therefore, we ...
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Open AccessCorrection: Increasing prevalence of malaria and acute dengue virus coinfection in Africa: a meta-analysis and meta-regression of cross-sectional studies
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Open AccessPerformance of ultra-sensitive malaria rapid diagnostic test to detect Plasmodium falciparum infection in pregnant women in Kinshasa, the Democratic Republic of the Congo
Low peripheral parasitaemia caused by sequestration of Plasmodium falciparum in the placenta hampers the diagnosis of malaria in pregnant women, leading to microscopy or conventional rapid diagnostic tests (RDTs)...
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Open AccessIncreasing prevalence of malaria and acute dengue virus coinfection in Africa: a meta-analysis and meta-regression of cross-sectional studies
Malaria and dengue fever are the leading causes of acute, undifferentiated febrile illness. In Africa, misdiagnosis of dengue fever as malaria is a common scenario. Through a systematic review of the published...
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Article
Open AccessPrion strains viewed through the lens of cryo-EM
Mammalian prions are lethal transmissible pathogens that cause fatal neurodegenerative diseases in humans and animals. They consist of fibrils of misfolded, host-encoded prion protein (PrP) which propagate thr...
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Open AccessLaboratory evaluation of the miniature direct-on-blood PCR nucleic acid lateral flow immunoassay (mini-dbPCR-NALFIA), a simplified molecular diagnostic test for Plasmodium
Point-of-care diagnosis of malaria is currently based on microscopy and rapid diagnostic tests. However, both techniques have their constraints, including poor sensitivity for low parasitaemias. Hence, more ac...
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Article
Should we respect parents’ views about which results to return from genomic sequencing?
Genomic sequencing (GS) is now well embedded in clinical practice. However, guidelines issued by professional bodies disagree about whether unsolicited findings (UF)—i.e., disease-causing changes found in the ...
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Article
Effects of Auditory LTP-Like Stimulation on Auditory Stimulus Processing
High-frequency electrical stimulation induces increases in synchronous transmission between pairs of neurons which persists for prolonged periods (long-term potentiation, LTP). Recent studies showed that senso...
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Article
Dopaminergic Receptors as Neuroimmune Mediators in Experimental Autoimmune Encephalomyelitis
The dopaminergic system plays an essential role in maintaining homeostasis between the central nervous system (CNS) and the immune system. Previous studies have associated imbalances in the dopaminergic system...
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Open AccessPain Monitoring Using Heart Rate Variability and Photoplethysmograph-Derived Parameters by Binary Logistic Regression
To construct a pain classification model using binary logistic regression to calculate pain probability and monitor pain based on heart rate variability (HRV) and photoplethysmography (PPG) parameters.
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A quality assessment tool for artificial intelligence-centered diagnostic test accuracy studies: QUADAS-AI
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Features of the Social Behavior of Mice after Prolonged Exposure to Psychoemotional and Infective Factors
We report here studies of the behavior of male mice of the inbred strain C57BL/6 after prolonged exposure to two factors – social stress and infections with Opisthorchis, a combination which is often seen in huma...
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Braylin induces a potent vasorelaxation, involving distinct mechanisms in superior mesenteric and iliac arteries of rats
Arterial hypertension is a risk factor for various cardiovascular and renal diseases, representing a major public health challenge. Although a wide range of treatment options are available for blood pressure c...
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Open AccessGenetic variation in the immune system and malaria susceptibility in infants: a nested case–control study in Nanoro, Burkina Faso
Genetic polymorphisms in the human immune system modulate susceptibility to malaria. However, there is a paucity of data on the contribution of immunogenetic variants to malaria susceptibility in infants, who ...
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Open AccessWhy psychiatry is different - challenges and difficulties in managing a nosocomial outbreak of coronavirus disease (COVID-19) in hospital care
Coronavirus disease (COVID-19) was officially declared a pandemic in March 2020. Many cases of COVID-19 are nosocomial, but to the best of our knowledge, no nosocomial outbreaks on psychiatric departments of s...