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  1. No Access

    Article

    Identification of a biological signature for schizophrenia in serum

    Biomarkers are now used in many areas of medicine but are still lacking for psychiatric conditions such as schizophrenia (SCZ). We have used a multiplex molecular profiling approach to measure serum concentrat...

    E Schwarz, P C Guest, H Rahmoune, L W Harris, L Wang, F M Leweke… in Molecular Psychiatry (2012)

  2. Article

    Open Access

    Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

    Cannabidiol is a component of marijuana that does not activate cannabinoid receptors, but moderately inhibits the degradation of the endocannabinoid anandamide. We previously reported that an elevation of anan...

    F M Leweke, D Piomelli, F Pahlisch, D Muhl, C W Gerth, C Hoyer… in Translational Psychiatry (2012)

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  3. No Access

    Article

    Impaired glycolytic response in peripheral blood mononuclear cells of first-onset antipsychotic-naive schizophrenia patients

    Little is known about the biological mechanisms underpinning the pathology of schizophrenia. We have analysed the proteome of stimulated and unstimulated peripheral blood mononuclear cells (PBMCs) from schizop...

    M Herberth, D Koethe, T M K Cheng, N D Krzyszton, S Schoeffmann… in Molecular Psychiatry (2011)

  4. No Access

    Article

    Global proteomic profiling reveals altered proteomic signature in schizophrenia serum

    Schizophrenia is one of the most severe psychiatric disorders affecting 1% of the world population. There is yet no empirical method to validate the diagnosis of the disease. The identification of an underlyin...

    Y Levin, L Wang, E Schwarz, D Koethe, F M Leweke, S Bahn in Molecular Psychiatry (2010)

  5. No Access

    Article

    Differential effects on T-cell function following exposure to serum from schizophrenia smokers

    Cigarette smoking is more prevalent in subjects with schizophrenia compared to those with other psychiatric disorders or the general population and could therefore affect molecular pathways that impact the pat...

    M Herberth, D N Krzyszton, D Koethe, M R Craddock, E Bulger… in Molecular Psychiatry (2010)

  6. No Access

    Article

    Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naïve schizophrenia patients

    P C Guest, L Wang, L W Harris, K Burling, Y Levin, A Ernst… in Molecular Psychiatry (2010)

  7. Article

    Erratum: Differential effects on T-cell function following exposure to serum from schizophrenia smokers

    Correction to: Molecular Psychiatry advance online publication 11 November 2008; doi: 10.1038/mp.2008.120 Following the online publication of the above article, the authors noted the following errors in Figure...

    M Herberth, D N Krzyszton, D Koethe, M R Craddock, E Bulger… in Molecular Psychiatry (2009)

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  8. No Access

    Article

    Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues

    Although some insights into the etiology of schizophrenia have been gained, an understanding of the illness at the molecular level remains elusive. Recent advances in proteomic profiling offer great promise fo...

    J T-J Huang, L Wang, S Prabakaran, M Wengenroth, H E Lockstone… in Molecular Psychiatry (2008)