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  1. No Access

    Article

    Myelin-associated oligodendrocytic basic protein-dependent myelin repair confers the long-lasting antidepressant effect of ketamine

    Ketamine exhibits rapid and sustained antidepressant effects. As decreased myelination has been linked to depression pathology, changes in myelination may be a pivotal mechanism underlying ketamine’s long-last...

    Chaoli Huang, Zifeng Wu, Di Wang, Youge Qu, Jichun Zhang… in Molecular Psychiatry (2023)

  2. Article

    Open Access

    Lateral septum-lateral hypothalamus circuit dysfunction in comorbid pain and anxiety

    Pain and anxiety comorbidities are a common health problem, but the neural mechanisms underlying comorbidity remain unclear. We propose that comorbidity implies that similar brain regions and neural circuits, ...

    Di Wang, **angyu Pan, Yu Zhou, Zifeng Wu, Kunpeng Ren, Hanyu Liu… in Molecular Psychiatry (2023)

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  3. Article

    Open Access

    miR-98-5p plays a critical role in depression and antidepressant effect of ketamine

    Ketamine has been demonstrated to be a rapid-onset and long-lasting antidepressant, but its underlying molecular mechanisms remain unclear. Recent studies have emerged microRNAs as important modulators for dep...

    Chaoli Huang, Yuanyuan Wang, Zifeng Wu, Jiali Xu, Ling Zhou… in Translational Psychiatry (2021)

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