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Article
Open AccessCorrection: Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis
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Article
Projections of summer light rain frequency in typical terrain over eastern China under wind speed constraint
The variation in near-surface wind speed is a key dynamic parameter in the orographic effect of precipitation over eastern China. In this study, we used the latest high-resolution outputs from six GCMs in CMIP...
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Article
Open AccessPositive effect of deep diaphragmatic breathing training on gastroesophageal reflux-induced chronic cough: a clinical randomized controlled study
To explore the efficacy of deep diaphragmatic breathing training (DEP) in patients with gastroesophageal reflux-induced chronic cough (GERC).
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Article
Open AccessDistinguishing benign and malignant thyroid nodules using plasma trimethylamine N-oxide, carnitine, choline and betaine
Trimethylamine N-oxide (TMAO), a gut microbiome–derived metabolite, and its precursors (carnitine, choline, betaine) have not been fully examined in relation to thyroid cancer (TC) risk. The aim of this study ...
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Article
Open AccessEffects of gelatin type and concentration on the preparation and properties of freeze-dried fish oil powders
The effects of gelatin type (porcine skin gelatin, PSG; bovine skin gelatin, BSG; fish gelatin, FG; or cold-water fish skin gelatin, CFG) and concentration on the preparation and properties of fish oil powders...
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Article
Numerical Analysis for Behavior of Stainless-Steel Web Cleat Connections at Elevated Temperatures
Stainless steel offers the advantages of excellent mechanical properties and exceptional corrosion resistance, making it a commonly used material in engineering. However, occasional fire incidents in engineeri...
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Article
Open AccessEffect of the smartphone application on caesarean section in women with overweight and obesity: a randomized controlled trial in China
The rate of caesarean section (CS) is increasing worldwide. While a CS can be life-saving when medically indicated, it can cause adverse health effects for both women and children. This trial aims to evaluate ...
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Article
Open AccessA randomized, double-blinded, placebo-controlled clinical trial of duloxetine hydrochloride enteric-coated tablets in the treatment of refractory chronic cough
Refractory cough, a chronic cough with an unclear diagnosis or poor treatment response. The symptoms are often stubborn and persistent, causing serious complications and lowering the patient's quality of life....
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Article
Two Typical Synoptic-Scale Weather Patterns of Dust Events over the Tibetan Plateau
Synoptic-scale weather systems play dominant roles in inducing high tropospheric dust over the Tibetan Plateau (TP). However, few studies have summarized the typical synoptic-scale weather patterns when high t...
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Article
Development of a Pt-graphene nanocomposite-based solid-phase extraction coupled with ultra-performance liquid chromatography–tandem mass spectrometry for the determination of carbamate pesticides in fish
In the present work, a potential solid-phase extraction (SPE) material based on graphene anchored with platinum nanoparticles (Pt-Graphene) was prepared and characterized by scanning electron micrographs and t...
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Article
Open AccessTween emulsifiers improved alginate-based dispersions and ionic crosslinked milli-sized capsules
The blending of surfactants might change the properties of alginate-based oil encapsulation preparations. Herein, the effects of Tween series (Tween 20, 40, 60, and 80) blending on the fish oil-encapsulated so...
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Article
Basketball motion video target tracking algorithm based on improved gray neural network
This article takes the basketball game video with high attention in sports video as an example to analyze the feature extraction of basketball game video, improve the gray neural network algorithm, and disasse...
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Article
Cancer Immunotherapy: Fecal Microbiota Transplantation Brings Light
Immunotherapy is revolutionizing tumor treatment by activating the immune response to tumors. Among them, immunotherapy represented by immune checkpoint inhibitors is considered to be a milestone in tumor trea...
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Article
Open AccessRecruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis
Synergies of transcription factors, chromatin modifiers and their target genes are vital for cell fate determination in human cancer. Although the importance of numerous epigenetic machinery for regulating gli...
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Article
Enhanced production of cordycepic acid from Cordyceps cicadae isolated from a wild environment
Cordyceps acid is an active component of Cordyceps cicadae and has a variety of medicinal uses, including anti-tumor effects, the prevention of cerebral hemorrhaging and myocardial infarction, and the inhibition ...
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Article
Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis
Nonalcoholic steatohepatitis (NASH) is a common chronic liver disease that is increasingly prevalent worldwide. Liver inflammation is an important contributor to disease progression from nonalcoholic fatty liv...
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Article
Open AccessThe efficacy of gabapentin for the treatment of refractory cough associated with interstitial lung disease: study protocol for a randomized, double-blind and placebo-controlled clinical trial
Gabapentin, a neurotransmitter modulator, is thought to treat refractory cough associated with interstitial lung disease by improving cough hypersensitivity.
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Article
Metabolomics reveals the mechanism of Antarctic yeast Rhodotorula mucliaginosa AN5 to cope with cadmium stress
Heavy metal pollution in Antarctica has far exceeded expectations. Antarctic yeast is widely present in polar marine environment. The mechanisms of metabolomics effect of heavy metal on polar yeast have not be...
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Map** Wind Speed Changes
Wind variability has a major impact on water cycles, wind energy, and natural hazards and disasters such as hurricanes and typhoons. In the past decades, the global and regional mean near-surface wind speed (s...
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Article
Open AccessYeasts from Chinese strong flavour Daqu samples: isolation and evaluation of their potential for fortified Daqu production
In total, 16 yeast were isolated from Chinese strong flavour Daqu samples and underwent RAPD analysis and identification. Totally, 11 different species were identified among these isolates including Saccharomyces...