2 Result(s)
within
Claire Legendre
English
Health Promotion and Disease Prevention
-
Article
Open AccessLow oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells
Overcoming resistance to treatment is an essential issue in many cancers including glioblastoma (GBM), the deadliest primary tumor of the central nervous system. As dependence on iron is a key feature of tumor...
-
Article
Open AccessA role for ceruloplasmin in the control of human glioblastoma cell responses to radiation
Glioblastoma (GB) is the most common and most aggressive malignant brain tumor. In understanding its resistance to conventional treatments, iron metabolism and related pathways may represent a novel avenue. As...
