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  1. Article

    Open Access

    Transcranial direct current stimulation–induced changes in motor cortical connectivity are associated with motor gains following ischemic stroke

    Understanding the response of the injured brain to different transcranial direct current stimulation (tDCS) montages may help explain the variable tDCS treatment results on poststroke motor gains. Cortical con...

    Chunfang Wang, **angli Yang, Dan Guo, Weiguang Huo, Ningbo Yu in Scientific Reports (2024)

  2. Article

    Open Access

    A Bacillus velezensis strain isolated from oats with disease-preventing and growth-promoting properties

    Endophytes have been shown to promote plant growth and health. In the present study, a Bacillus velezensis CH1 (CH1) strain was isolated and identified from high-quality oats, which was capable of producing indol...

    Chao Cheng, Shaofeng Su, Suling Bo, Chengzhong Zheng, Chunfang Liu in Scientific Reports (2024)

  3. Article

    Open Access

    Unrecognized extensive charge of microbial gas in the Junggar basin

    Different from the Qaidam basin with about 320 billion m3 microbial gas, only limited microbial gases were found from the Junggar basin with similarly abundant type III kerogen. To determine whether microbial gas...

    Hao Zhang, Chunfang Cai, **aomin Mei, Daowei Wang, Dawei Liu in Scientific Reports (2024)

  4. Article

    Open Access

    Intra-articular injection of miRNA-1 agomir, a novel chemically modified miRNA agonists alleviates osteoarthritis (OA) progression by downregulating Indian hedgehog in rats

    Our objective in this study is to determine whether intra-articular injection of miRNA-1 can attenuate the progression of OA in rats by down regulating Ihh. Knee chondrocytes were isolated from male Sprague–Da...

    Pengcui Li, Yangyang Gao, Raorao Zhou, **anda Che, Hang Wang in Scientific Reports (2024)

  5. Article

    Open Access

    SEGCN: a subgraph encoding based graph convolutional network model for social bot detection

    Message passing neural networks such as graph convolutional networks (GCN) can jointly consider various types of features for social bot detection. However, the expressive power of GCN is upper-bounded by the ...

    Feng Liu, Zhenyu Li, Chunfang Yang, Daofu Gong, Haoyu Lu, Fenlin Liu in Scientific Reports (2024)

  6. Article

    Open Access

    PI3K/Akt signaling pathway mediates the effect of low-dose boron on barrier function, proliferation and apoptosis in rat intestinal epithelial cells

    Boron is an essential trace element with roles in growth, development, and physiological functions; however, its mechanism of action is still unclear. In this study, the regulatory roles of the PI3K/Akt signal...

    Shuqin Chen, Jialiang Huang, Ting Liu, Feng Zhang, Chunfang Zhao in Scientific Reports (2024)

  7. Article

    Open Access

    Comprehensive analysis reveals potential therapeutic targets and an integrated risk stratification model for solitary fibrous tumors

    Solitary fibrous tumors (SFTs) are rare mesenchymal tumors with unpredictable evolution and with a recurrence or metastasis rate of 10-40%. Current medical treatments for relapsed SFTs remain ineffective. Here...

    Ren**g Zhang, Yang Yang, Chunfang Hu, Mayan Huang, Wenjian Cen in Nature Communications (2023)

  8. Article

    Open Access

    Association between excessive fetal growth and maternal cancer in Shanghai, China: a large, population-based cohort study

    The prevalence of high birth weight or large for gestational age (LGA) infants is increasing, with increasing evidence of pregnancy-related factors that may have long-term impacts on the health of the mother a...

    Naisi Qian, Qing Yang, Lei Chen, Shan **, Jiaying Qiao, Renzhi Cai in Scientific Reports (2023)

  9. Article

    Open Access

    From comparative gene content and gene order to ancestral contigs, chromosomes and karyotypes

    To reconstruct the ancestral genome of a set of phylogenetically related descendant species, we use the raccroche pipeline for organizing a large number of generalized gene adjacencies into contigs and then into ...

    Qiaoji Xu, Lingling **, Chunfang Zheng, **aomeng Zhang in Scientific Reports (2023)

  10. Article

    Open Access

    Scalable and switchable CO2-responsive membranes with high wettability for separation of various oil/water systems

    Smart membranes with responsive wettability show promise for controllably separating oil/water mixtures, including immiscible oil-water mixtures and surfactant-stabilized oil/water emulsions. However, the memb...

    Yangyang Wang, Shaokang Yang, **gwei Zhang, Zhuo Chen, Bo Zhu in Nature Communications (2023)

  11. Article

    Open Access

    Bioinformatics construction and experimental validation of a cuproptosis-related lncRNA prognostic model in lung adenocarcinoma for immunotherapy response prediction

    Cuproptosis is a newly form of cell death. Cuproptosis related lncRNA in lung adenocarcinoma (LUAD) has also not been fully elucidated. In the present study, we aimed to construct a prognostic signature based ...

    Linfeng Li, Qidong Cai, Zeyu Wu, **zhe Li, Wolong Zhou, Liqing Lu in Scientific Reports (2023)

  12. Article

    Open Access

    Development and validation of a novel immune-related prognostic signature in lung squamous cell carcinoma patients

    Lung Squamous Cell Carcinoma (LUSC) is an aggressive malignancy with limited therapeutic options. The response to immune therapy is a determining factor for the prognosis of LUSC patients. This study aimed to ...

    **anyu Liu, Deze Zhao, Yunhan Shan, Weifang Cui, Qun **e in Scientific Reports (2022)

  13. Article

    Open Access

    Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation

    Xanthone-containing natural products display diverse pharmacological properties. The biosynthetic mechanisms of the xanthone formation have not been well documented. Here we show that the flavoprotein monooxyg...

    Chunfang Yang, Li** Zhang, Wenjun Zhang, Chunshuai Huang in Nature Communications (2022)

  14. Article

    Open Access

    Flavin-enabled reductive and oxidative epoxide ring opening reactions

    Epoxide ring opening reactions are common and important in both biological processes and synthetic applications and can be catalyzed in a non-redox manner by epoxide hydrolases or reductively by oxidoreductase...

    Bidhan Chandra De, Wenjun Zhang, Chunfang Yang, Attila Mándi in Nature Communications (2022)

  15. Article

    Open Access

    Author Correction: Association of adverse birth outcomes with in vitro fertilization after controlling infertility factors based on a singleton live birth cohort

    Huiting Yu, Zhou Liang, Renzhi Cai, Shan **, Tian **a, Chunfang Wang in Scientific Reports (2022)

  16. Article

    Open Access

    Association of adverse birth outcomes with in vitro fertilization after controlling infertility factors based on a singleton live birth cohort

    Infants conceived with in vitro fertilization (IVF) are exposed to underlying infertility and the IVF process. High risks of adverse birth outcomes (ABOs) were observed among these infants, including preterm b...

    Huiting Yu, Zhou Liang, Renzhi Cai, Shan **, Tian **a, Chunfang Wang in Scientific Reports (2022)

  17. Article

    Open Access

    Co-functioning of 2AP precursor amino acids enhances 2-acetyl-1-pyrroline under salt stress in aromatic rice (Oryza sativa L.) cultivars

    Aromatic rice (Oryza sativa) fetches a premium price due to the pleasant aroma. The major aroma compound 2-acetyl-1-pyrroline (2AP) has been found to be enhanced under stress. This condition can be considered to ...

    N. Renuka, Vitthal T. Barvkar, Zahid Ansari, Chunfang Zhao in Scientific Reports (2022)

  18. Article

    Open Access

    Diamondoids and thiadiamondoids generated from hydrothermal pyrolysis of crude oil and TSR experiments

    Diamondoid compounds are widely used to reflect thermal maturation of high mature source rocks or oils and oil cracking extents. However, diamondoids and thiadiamondoids were demonstrated to have newly been ge...

    Yanyan Peng, Chunfang Cai, Chenchen Fang, Liangliang Wu, **zhong Liu in Scientific Reports (2022)

  19. Article

    Open Access

    Fabrication and evaluation of slow-release lignin-based avermectin nano-delivery system with UV-shielding property

    Nanopesticide is one of the best pesticide formulation technologies to overcome the disadvantages of traditional pesticides, which has received great attention from the international community. Using high-spee...

    Dongmei Mo, **angying Li, Yong Chen, Yang Jiang, Chunfang Gan in Scientific Reports (2021)

  20. Article

    Open Access

    Author Correction: A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite

    Laura-Oana Albulescu, Chunfang **e, Stuart Ainsworth in Nature Communications (2021)

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