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  1. No Access

    Article

    Endothelin-1 enhances acid-sensing ion channel currents in rat primary sensory neurons

    Endothelin-1 (ET-1), an endogenous vasoactive peptide, has been found to play an important role in peripheral pain signaling. Acid-sensing ion channels (ASICs) are key sensors for extracellular protons and con...

    Lei Wu, Ting-ting Liu, Ying **, Shuang Wei, Chun-yu Qiu… in Acta Pharmacologica Sinica (2020)

  2. No Access

    Article

    Enhancement of acid-sensing ion channel activity by metabotropic P2Y UTP receptors in primary sensory neurons

    Peripheral purinergic signaling plays an important role in nociception. Increasing evidence suggests that metabotropic P2Y receptors are also involved, but little is known about the underlying mechanism. Herei...

    Cuixia Ren, **ong Gan, **g Wu, Chun-Yu Qiu, Wang-** Hu in Purinergic Signalling (2016)