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  1. No Access

    Article

    Differential DNA Methylation Status Between Human Preadipocytes and Mature Adipocytes

    Obesity is a multifactorial disease resulting from interactions between susceptibility genes, psychosocial, and environmental factors. However, it is becoming evident that interindividual differences in obesit...

    **-gai Zhu, Li **a, Chen-bo Ji, Chun-mei Zhang… in Cell Biochemistry and Biophysics (2012)

  2. No Access

    Article

    Overexpression of TFAM Protects 3T3-L1 Adipocytes from NYGGF4 (PID1) Overexpression-Induced Insulin Resistance and Mitochondrial Dysfunction

    NYGGF4, also known as phosphotyrosine interaction domain containing 1(PID1), is a recently discovered gene which is involved in obesity-related insulin resistance (IR) and mitochondrial dysfuncti...

    Chun-Mei Shi, Guang-Feng Xu, Lei Yang, Zi-Yi Fu… in Cell Biochemistry and Biophysics (2013)

  3. No Access

    Article

    MiR-335, an Adipogenesis-Related MicroRNA, is Involved in Adipose Tissue Inflammation

    During the development of obesity, adipose tissue releases a host of different adipokines and inflammatory cytokines, such as leptin, resistin, tumor necrosis factor α (TNF-α), Interleukin-6 (IL-6), and adipon...

    Lu Zhu, Ling Chen, Chun-Mei Shi, Guang-Feng Xu… in Cell Biochemistry and Biophysics (2014)

  4. No Access

    Article

    Knockdown of LYRM1 Rescues Insulin Resistance and Mitochondrial Dysfunction Induced by FCCP in 3T3-L1 Adipocytes

    LYR motif-containing 1 (LYRM1) was recently discovered to be involved in adipose tissue homeostasis and obesity-associated insulin resistance. We previously demonstrated that LYRM1 overexpression might contribute...

    Min Zhang, Zhen-Ying Qin, Yong-mei Dai, Yu-Mei Wang… in Cell Biochemistry and Biophysics (2014)

  5. No Access

    Article

    TNF-α, IL-6, and Leptin Increase the Expression of miR-378, an Adipogenesis-Related microRNA in Human Adipocytes

    Obesity has become a global public health problem associated with complications including type 2 diabetes, cardiovascular disease, and several cancers. Adipocyte differentiation (adipogenesis) plays an importa...

    Lu-lian Xu, Chun-mei Shi, Guang-feng Xu, Ling Chen… in Cell Biochemistry and Biophysics (2014)