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138 Result(s)
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Article
Open AccessNeferine inhibits BMECs pyroptosis and maintains blood–brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α
Blood–brain barrier disruption is a critical pathological event in the progression of ischemic stroke (IS). Most studies regarding the therapeutic potential of neferine (Nef) on IS have focused on neuroprotect...
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Open AccessInvestigation of metal concentration distribution and corresponding health exposure assessment of fabricated metal product manufacturers
The fabricated metal product industries were identified as producers of variable and heterogeneous pollution. Workers in these manufacturing facilities are exposed to multiple pollutants present at variable co...
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Article
Open AccessConstructing regulable supports via non-stoichiometric engineering to stabilize ruthenium nanoparticles for enhanced pH-universal water splitting
Establishing appropriate metal-support interactions is imperative for acquiring efficient and corrosion-resistant catalysts for water splitting. Herein, the interaction mechanism between Ru nanoparticles and a...
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Open AccessPhotooxidation triggered ultralong afterglow in carbon nanodots
It remains a challenge to obtain biocompatible afterglow materials with long emission wavelengths, durable lifetimes, and good water solubility. Herein we develop a photooxidation strategy to construct near-in...
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Open AccessEnhanced formation of methane hydrate from active ice with high gas uptake
Gas hydrates provide alternative solutions for gas storage & transportation and gas separation. However, slow formation rate of clathrate hydrate has hindered their commercial development. Here we report a for...
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Open AccessH3.1K27me1 loss confers Arabidopsis resistance to Geminivirus by sequestering DNA repair proteins onto host genome
The H3 methyltransferases ATXR5 and ATXR6 deposit H3.1K27me1 to heterochromatin to prevent genomic instability and transposon re-activation. Here, we report that atxr5 atxr6 mutants display robust resistance to G...
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Open AccessBroad and colossal edge supercurrent in Dirac semimetal Cd3As2 Josephson junctions
Edge supercurrent has attracted great interest recently due to its crucial role in achieving and manipulating topological superconducting states. Proximity-induced superconductivity has been realized in quantu...
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Article
Open AccessIRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice
Cardiac fibrosis is a common feature of chronic heart failure. Iroquois homeobox (IRX) family of transcription factors plays important roles in heart development; however, the role of IRX2 in cardiac fibrosis ...
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Article
Open AccessFunctional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia
The genus Salvia L. (Lamiaceae) comprises myriad distinct medicinal herbs, with terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs), such as tanshinones and carnosic acids, ...
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Article
Open AccessIdentification of autophagy-associated circRNAs in sepsis-induced cardiomyopathy of mice
Circular RNAs (circRNAs) play a role in sepsis-related autophagy. However, the role of circRNAs in autophagy after sepsis-induced cardiomyopathy (SICM) is unknown, so we explored the circRNA expression profile...
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Open AccessA maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis
The unique dumbbell-shape of grass guard cells (GCs) is controlled by their cell walls which enable their rapid responses to the environment. The molecular mechanisms regulating the synthesis and assembly of G...
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Open AccessFAT-switch-based quantitative S-nitrosoproteomics reveals a key role of GSNOR1 in regulating ER functions
Reversible protein S-nitrosylation regulates a wide range of biological functions and physiological activities in plants. However, it is challenging to quantitively determine the S-nitrosylation targets and dy...
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Open AccessCoherent control of an ultrabright single spin in hexagonal boron nitride at room temperature
Hexagonal boron nitride (hBN) is a remarkable two-dimensional (2D) material that hosts solid-state spins and has great potential to be used in quantum information applications, including quantum networks. Howe...
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Open AccessThree-dimensional covalent organic frameworks with pto and mhq-z topologies based on Tri- and tetratopic linkers
Three-dimensional (3D) covalent organic frameworks (COFs) possess higher surface areas, more abundant pore channels, and lower density compared to their two-dimensional counterparts which makes the development...
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Open AccessThe impact of perceived risk of online takeout packaging and the moderating role of educational level
With the rapid development of e-commerce and the impact of COVID-19, online takeout has become the first choice of more and more consumers. Previous research has indicated that food packaging is of great signi...
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Open AccessEpitaxial growth of highly symmetrical branched noble metal-semiconductor heterostructures with efficient plasmon-induced hot-electron transfer
Epitaxial growth is one of the most commonly used strategies to precisely tailor heterostructures with well-defined compositions, morphologies, crystal phases, and interfaces for various applications. However,...
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Article
Open AccessSingle-cell transcriptomes reveal heterogeneity of chlorine-induced mice acute lung injury and the inhibitory effect of pentoxifylline on ferroptosis
To investigate the effect of pentoxifylline (PTX) on Chlorine (Cl2)-induced acute lung injury (ALI) by single-cell RNA sequencing (scRNA-seq). Female BALB/c mice were exposed to Cl2 at 400 ppm for 15 min. H&E sta...
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Open AccessUnderstanding the sulphur-oxygen exchange process of metal sulphides prior to oxygen evolution reaction
Dynamic reconstruction of metal sulphides during electrocatalytic oxygen evolution reaction (OER) has hampered the acquisition of legible evidence for comprehensively understanding the phase-transition mechani...
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Open AccessThe built-in electric field across FeN/Fe3N interface for efficient electrochemical reduction of CO2 to CO
Nanostructured metal-nitrides have attracted tremendous interest as a new generation of catalysts for electroreduction of CO2, but these structures have limited activity and stability in the reduction condition. ...
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Open AccessComplete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases
Poly(butylene adipate-co-terephthalate) (PBAT), a polyester made of terephthalic acid (TPA), 1,4-butanediol, and adipic acid, is extensively utilized in plastic production and has accumulated globally as envir...