-
Article
Open AccessIntegrated molecular and multiparametric MRI map** of high-grade glioma identifies regional biologic signatures
Sampling restrictions have hindered the comprehensive study of invasive non-enhancing (NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present an integrated multi-omic analysis...
-
Article
Open AccessMolecular subtypes of ALS are associated with differences in patient prognosis
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood clinical heterogeneity, underscored by significant differences in patient age at onset, symptom progression, therapeuti...
-
Article
Open AccessN6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
Many of the regulatory features governing erythrocyte specification, maturation, and associated disorders remain enigmatic. To identify new regulators of erythropoiesis, we utilize a functional genomic screen ...