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  1. Article

    Open Access

    Role of enzalutamide in primary and recurrent non-metastatic hormone sensitive prostate cancer: a systematic review of prospective clinical trials

    Enzalutamide, a second-generation androgen receptor inhibitor, is indicated for the treatment of metastatic disease, as well as in the treatment of non-metastatic castration resistant prostate cancer (PCa). Th...

    Mohamed Shelan, Vérane Achard, Felix Appiagyei in Prostate Cancer and Prostatic Diseases (2024)

  2. Article

    Open Access

    Outcomes of relapsed clinical stage I versus de novo metastatic testicular cancer patients: an analysis of the IGCCCG Update database

    Active surveillance after orchiectomy is the preferred management in clinical stage I (CSI) germ-cell tumours (GCT) associated with a 15 to 30% relapse rate.

    Jakob Lauritsen, Nicolas Sauvé, Alexey Tryakin, Di Maria Jiang in British Journal of Cancer (2023)

  3. Article

    Open Access

    Excellent survival in relapsed stage I testicular cancer

    Two thirds of patients with germ-cell cancer (GCC) present as clinical stage I (CSI). Following orchiectomy, active surveillance (AS) has become their standard management. However, 15–50% of patients eventuall...

    Philip Speicher, Christian D. Fankhauser, Anja Lorch, Davide Ardizzone in BMC Cancer (2023)

  4. Article

    Open Access

    Is conservative management safe in patients with acute ureterolithiasis and perirenal stranding?

    In patients presenting with ureterolithiasis, perirenal stranding is frequently observed in non-contrast computed tomography. Because perirenal stranding may be caused by tears in the collecting system, previo...

    Nico C. Grossmann, Davide Ardizzone, Thomas Hermanns, Etienne X. Keller in Urolithiasis (2023)

  5. No Access

    Article

    Lymphovascular and perineural invasion are risk factors for inguinal lymph node metastases in men with T1G2 penile cancer

    To analyse the risk of inguinal lymph node (ILN) metastases in T1G2 penile cancer stratified by lymphovascular invasion (LVI), perineural invasion (PNI) and tumour size.

    Christian D. Fankhauser, Hielke M. de Vries in Journal of Cancer Research and Clinical On… (2022)

  6. Article

    Open Access

    Preoperative smoking cessation program in patients undergoing intermediate to high-risk surgery: a randomized, single-blinded, controlled, superiority trial

    At present, effectively implementing smoking cessation programs in the health care system constitutes a major challenge. A unique opportunity to initiate smoking cessation focuses on smokers scheduled for surg...

    Christian D. Fankhauser, Andres Affentranger, Beatrice Cortonesi, Urs Jeker in Trials (2022)

  7. No Access

    Article

    Minimally invasive retroperitoneal lymph node dissection for men with testis cancer: a retrospective cohort study of safety and feasibility

    To describe the perioperative safety, functional and immediate post-operative oncological outcomes of minimally invasive RPLND (miRPLND) for testis cancer.

    Christian D. Fankhauser, Luca Afferi, Sean P. Stroup in World Journal of Urology (2022)

  8. Article

    Open Access

    Risk factors for concomitant positive midstream urine culture in patients presenting with symptomatic ureterolithiasis

    In patients with symptomatic ureterolithiasis, immediate treatment of concomitant urinary tract infection (UTI) may prevent sepsis. However, urine cultures require at least 24 h to confirm or exclude UTI, and ...

    Nico C. Grossmann, Victor M. Schuettfort, Jeannine Betschart in Urolithiasis (2022)

  9. No Access

    Article

    Detection of recurrences using serum miR-371a-3p during active surveillance in men with stage I testicular germ cell tumours

    MiR-371a-3p predicts the presence of a macroscopic non-teratomatous germ cell tumour (GCT). We hypothesised that miR-371a-3p can also detect recurrence during active surveillance (AS) of stage I GCT.

    Christian D. Fankhauser, Ailsa J. Christiansen in British Journal of Cancer (2022)

  10. No Access

    Article

    Immediate radical cystectomy versus BCG immunotherapy for T1 high-grade non-muscle-invasive squamous bladder cancer: an international multi-centre collaboration

    To compare cancer-specific mortality (CSM) and overall mortality (OM) between immediate radical cystectomy (RC) and Bacillus Calmette–Guérin (BCG) immunotherapy for T1 squamous bladder cancer (BCa).

    Chiara Lonati, Luca Afferi, Andrea Mari, Andrea Minervini in World Journal of Urology (2022)

  11. Article

    Open Access

    68Ga-PSMA-11 PET imaging in patients with ongoing androgen deprivation therapy for advanced prostate cancer

    Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET) imaging significantly improved the detection of recurrent prostate cancer (PCa). However, the value of PSMA PET imaging in ...

    Saskia Fassbind, Daniela A. Ferraro, Jean-Jacques Stelmes in Annals of Nuclear Medicine (2021)

  12. No Access

    Article

    Prognostic value of unifocal and multifocal positive surgical margins in a large series of robot-assisted radical prostatectomy for prostate cancer

    To evaluate the prognostic value of positive surgical margins (PSM) focality for the prediction of biochemical recurrence (BCR) in patients undergoing robotic-assisted radical prostatectomy (RARP) for prostate...

    Etienne Xavier Keller, Jacqueline Bachofner in World Journal of Urology (2019)

  13. No Access

    Article

    Is loss of power output due to laser fiber degradation still an issue during prostate vaporization using the 180 W GreenLight XPS laser?

    To investigate whether heat-induced fiber degradation and loss of power output, which occurred during GreenLight laser vaporization (LV) of the prostate using the first- and second-generation 80 and 120 W lase...

    Thomas Hermanns, Nico C. Grossmann, Marian S. Wettstein in World Journal of Urology (2019)

  14. No Access

    Article

    Prediction of successful shock wave lithotripsy with CT: a phantom study using texture analysis

    To apply texture analysis (TA) in computed tomography (CT) of urinary stones and to correlate TA findings with the number of required shockwaves for successful shock wave lithotripsy (SWL).

    Manoj Mannil, Jochen von Spiczak, Thomas Hermanns, Hatem Alkadhi in Abdominal Radiology (2018)

  15. No Access

    Article

    Prostate volume reduction following pure transurethral bipolar plasma vaporization and conventional transurethral resection of the prostate: a prospective investigation using transrectal 3D ultrasound volumetry

    To evaluate and compare postoperative changes in prostate volume and clinical outcome after bipolar plasma vaporization (BPV) and conventional transurethral resection of the prostate (TURP).

    Benedikt Kranzbühler, Oliver Gross, Christian D. Fankhauser in World Journal of Urology (2017)

  16. No Access

    Article

    Absorption of irrigation fluid during XPS™ GreenLight laser vaporization of the prostate: results from a prospective breath ethanol monitoring study

    To assess whether and to what extent irrigation fluid absorption occurs during laser vaporization (LV) of the prostate using the 180 W XPS™ GreenLight laser.

    Marian S. Wettstein, Cédric Poyet, Nico C. Grossmann in World Journal of Urology (2016)

  17. No Access

    Article

    Predictive value of low tube voltage and dual-energy CT for successful shock wave lithotripsy: an in vitro study

    This study investigates the capabilities of low tube voltage computed tomography (CT) and dual-energy CT (DECT) for predicting successful shock wave lithotripsy (SWL) of urinary stones in vitro. A total of 33 ...

    Remo Largo, Paul Stolzmann, Christian D. Fankhauser, Cédric Poyet in Urolithiasis (2016)