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  1. Article

    Open Access

    Plasma proteomic associations with genetics and health in the UK Biobank

    The Pharma Proteomics Project is a precompetitive biopharmaceutical consortium characterizing the plasma proteomic profiles of 54,219 UK Biobank participants. Here we provide a detailed summary of this initiat...

    Benjamin B. Sun, Joshua Chiou, Matthew Traylor, Christian Benner, Yi-Hsiang Hsu in Nature (2023)

  2. No Access

    Article

    Map** genomic loci implicates genes and synaptic biology in schizophrenia

    Schizophrenia has a heritability of 60–80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 con...

    Vassily Trubetskoy, Antonio F. Pardiñas, Ting Qi, Georgia Panagiotaropoulou in Nature (2022)

  3. Article

    Open Access

    Exome sequencing and analysis of 454,787 UK Biobank participants

    A major goal in human genetics is to use natural variation to understand the phenotypic consequences of altering each protein-coding gene in the genome. Here we used exome sequencing1 to explore protein-altering ...

    Joshua D. Backman, Alexander H. Li, Anthony Marcketta, Dylan Sun, Joelle Mbatchou in Nature (2021)