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  1. Article

    Open Access

    Correction: BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis

    Chongbiao Huang, Hui Li, Yang Xu, Chao Xu in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis

    VEGF inhibitors are one of the most successful antiangiogenic drugs in the treatment of many solid tumors. Nevertheless, pancreatic adenocarcinoma (PAAD) cells can reinstate tumor angiogenesis via activation o...

    Chongbiao Huang, Hui Li, Yang Xu, Chao Xu in Signal Transduction and Targeted Therapy (2023)

  3. Article

    Open Access

    Irbesartan overcomes gemcitabine resistance in pancreatic cancer by suppressing stemness and iron metabolism via inhibition of the Hippo/YAP1/c-Jun axis

    Chemoresistance is the main reason for the poor prognosis of pancreatic ductal adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and compounds to reverse chemotherapeutic resistance.

    Tianxing Zhou, Yongjie **e, Xupeng Hou in Journal of Experimental & Clinical Cancer … (2023)

  4. Article

    Open Access

    ESE3-positive PSCs drive pancreatic cancer fibrosis, chemoresistance and poor prognosis via tumour–stromal IL-1β/NF–κB/ESE3 signalling axis

    Desmoplastic stroma, a feature of pancreatic ductal adenocarcinoma (PDAC), contains abundant activated pancreatic stellate cells (PSCs). How PSCs promote PDAC progression remains incompletely understood.

    Tiansuo Zhao, Di **ao, Fanjie **, Xugang Sun, Jie Yu in British Journal of Cancer (2022)

  5. No Access

    Article

    Usefulness of the neutrophil-to-lymphocyte ratio in predicting lymph node metastasis in patients with non-small cell lung cancer

    Preoperative neutrophil-to-lymphocyte ratio (NLR) is a new hotspot for its prognostic significance in many types of cancers. In this study, a novel diagnosing model—the combination of enhanced contrast compute...

    Chongbiao Huang, Jie Yue, Zengxun Li, Na Li, **kun Zhao, Daliang Qi in Tumor Biology (2015)