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Article
Open AccessBilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results
Gene therapy is a promising approach for hereditary deafness. We recently showed that unilateral AAV1-hOTOF gene therapy with dual adeno-associated virus (AAV) serotype 1 carrying human OTOF transgene is safe and...
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Article
Transcriptome and histopathology analyses of the gills of Eriocheir sinensis provide novel insights into the molecular mechanism of Pb stress
The Chinese mitten crab (Eriocheir sinensis) is an important aquatic economic species in China, which is sensitive to many toxicants that are likely to occur in the environment and is usually used as the bio-indi...
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Article
Perturbations of Moore-Penrose inverse and dual Moore-Penrose generalized inverse
In this paper, we present explicit expressions for the Moore-Penrose inverse of the perturbation matrix under the rank condition in the real field. Then we estimate the error between Moore-Penrose inverse and ...
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Article
Dual r-rank decomposition and its applications
In this paper, we introduce the dual r-rank decomposition of the dual matrix, get its existence conditions and equivalent forms of the decomposition. Then we derive some characteristics of dual Moore–Penrose gene...
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Article
Open AccessThe pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice
Mutations in GJB2 (Gap junction protein beta 2) are the most common genetic cause of non-syndromic hereditary deafness in humans, especially the 35delG and 235delC mutations. Owing to the homozygous lethality of
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Article
Path connectedness of the efficient solution set for generalized vector quasi-equilibrium problems
In this paper, the efficient solution set for generalized vector quasi-equilibrium problems is investigated. By means of the linear scalarization method, we establish the path connectedness of the efficient so...
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Article
Open AccessComparative transcriptome analysis provides insights into the molecular mechanisms of high-frequency hearing differences between the sexes of Odorrana tormota
Acoustic communication is important for the survival and reproduction of anurans and masking background noise is a critical factor for their effective acoustic communication. Males of the concave-eared frog (Odor...
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Article
Impermeability Research of Autoclaved Propylene Oxide Sludge Shell-aggregate Concrete
We aimed to reuse the propylene oxide sludge (POS). Propylene oxide sludge shell-aggregate (POSS-A) and propylene oxide sludge gradient shell-aggregate (POSGS-A) whose main hydrated phase is tobermorite were s...
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Article
Open AccessPreventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing
CRISPR/RfxCas13d (CasRx) editing system can specifically and precisely cleave single-strand RNAs, which is a promising treatment for various disorders by downregulation of related gene expression. Here, we tes...
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Article
SYNTHESIS AND CHARACTERIZATION OF ORDERED MESOPOROUS MCM-41 FROM NATURAL CHLORITE AND ITS APPLICATION IN METHYLENE BLUE ADSORPTION
Mesoporous materials have a wide range of applications in the fields of nanotechnology, biotechnology, information technology, and medicine, but historically, the resource materials used for their synthesis ha...
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Article
Synthesis and characterization of hyperbranched polymer with epoxide-terminated group and application as modifier for epoxy/polyamide system
Hyperbranched polymer with epoxide-terminated group was synthesized through end-cap** reaction between hyperbranched polymer with hydroxyl-terminated group and epichlorohydrin. The chemical structure of the ...
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Article
Mechanical characterization of epoxy composites with glass fibers grafted by hyperbranched polymer with amino terminal groups
Glass fibers grafted by hyperbranched polymer with amino terminal group, GFs-HBPA, were incorporated into an epoxy matrix to prepare a high-performance composite. Mechanical characterization of epoxy-based com...
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Article
Synergic improvement of DGEBA/CSP/HBP composite on mechanical behavior
Hyperbranched polymer with amino end groups (HBPA) and core-shell particle (CSP, which is fabricated through grafting HBPA onto the surface of silica nanoparticle) were incorporated into an epoxy matrix to fab...
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Article
The effect of core–shell particles on the mechanical performance of epoxy resins modified with hyperbranched polymers
A novel core–shell particle that consists of epoxide-terminated hyperbranched polymer (HBP) and silica nanoparticles was incorporated into an epoxy/hydroxyl-terminated HBP blend to fabricate a high-performance...
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Article
The effect of amino-terminated hyperbranched polymers on the impact resistance of epoxy resins
A novel amino-terminated hyperbranched polymer (ATHBP) was synthesized through the end-cap** reaction between hyperbranched polymer with hydroxyl group (HBPH) and diethylenetriamine. The chemical structure o...
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Article
Investigations on mechanical characteristics of glass fiber reinforced epoxy composite modified with amino-terminated hyperbranched polymer
Glass fiber, GF, which was first hydroxylated and silanized, was incorporated into epoxy resin modified with amino-terminated hyperbranched polymer (ATHBP) to obtain high performance composite. The effects of ...
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Article
Enhancing the mechanical properties of epoxy resin by addition of an amino-terminated hyperbranched polymer grown on glass fiber
In this study, glass fiber (GF) was grafted by an amino-terminated hyperbranched polymer (ATHBP). The structure of GF-ATHBP was characterized by attenuated total internal reflectance infrared spectroscopy, 1H nuc...
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Article
Synthesis and characterization of amino-terminated hyperbranched polymer and its effect on impact resistance of epoxy resin thermosets
Amino-terminated hyperbranched polymer (HBP-NH2) was synthesized from diethylenetriamine (DETA) and methyl acrylate (MA) by melt polycondensation through AB3 and AB2 route, and its chemical structure was characte...
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Article
Fe-MCM-41 from Coal-Series Kaolin as Catalysts for the Selective Catalytic Reduction of NO with Ammonia
Fe-MCM-41, one kind of high-ordered mesoporous materials catalysts, with molar ratio of Fe/Si = 0.01-0.1, was synthesized by hydrothermal method from coal-series kaolin. Fe-MCM-41 catalysts were characterized ...
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Article
Preparation of TiO2/Al-MCM-41 mesoporous materials from coal-series kaolin and photodegradation of methyl orange
TiO2/Al-MCM-41 mesoporous materials were prepared via sol-gel method by loading titania onto Al-MCM-41 mesoporous molecular sieve by hydrothermal treatment from coal-series kaolin as raw material. The TiO2/Al-MCM...
