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  1. Article

    Open Access

    Urinary beta 3-adrenoceptor as a diagnostic biomarker for overactive bladder in women

    This study was to investigate urinary beta 3-adrenoceptor concentration as a biomarker for overactive bladder (OAB) and predictor of treatment outcomes in women receiving the beta 3-adrenoceptor agonist mirabe...

    Ching-Chung Liang, Wu-Chiao Hsieh, Tsia-Shu Lo, Ting-Xuan Huang in Scientific Reports (2023)

  2. No Access

    Article

    Correlation between overactive bladder and detrusor overactivity: a retrospective study

    The primary objective of this study is to determine the prevalence of overactive bladder (OAB) and detrusor overactivity (DO) in female patients who were referred for urodynamic study (UDS) because of lower ur...

    Ting-Xuan Huang, Tsia-Shu Lo, Hsiao-Jung Tseng in International Urogynecology Journal (2023)

  3. Article

    Open Access

    Human amniotic fluid stem cells can alleviate detrusor dysfunction caused by bladder outlet obstruction in rats

    The present study examined whether bladder detrusor dysfunction due to partial bladder outlet obstruction (pBOO) could be improved after the treatment of human amniotic fluid stem cells (hAFSCs). 72 female rat...

    Ching-Chung Liang, Wen-Chu Huang, Steven W. Shaw, Yung-Hsin Huang in Scientific Reports (2022)

  4. Article

    Open Access

    Induced pluripotent stem cells can improve thrombolytic effect of low-dose rt-PA after acute carotid thrombosis in rat

    Intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) is the standard treatment for acute ischemic stroke. Standard-dose rt-PA (0.9 mg/kg) is known to achieve good recanalization but ...

    Hsi-Lung Hsieh, Ching-Chung Liang, Cheng-You Lu in Stem Cell Research & Therapy (2021)

  5. No Access

    Article

    Pregnancy weight gain may affect perinatal outcomes, quality of life during pregnancy, and child-bearing expenses: an observational cohort study

    We aimed to examine the effect of gestational weight gain (GWG) on perinatal outcomes, quality of life (QoL) during pregnancy, and medical costs of childbirth.

    Ching-Chung Liang, Minston Chao, Shuenn-Dhy Chang in Archives of Gynecology and Obstetrics (2021)

  6. Article

    Open Access

    Prenatal transplantation of human amniotic fluid stem cell could improve clinical outcome of type III spinal muscular atrophy in mice

    Spinal muscular atrophy (SMA) is a single gene disorder affecting motor function in uterus. Amniotic fluid is an alternative source of stem cell to ameliorate SMA. Therefore, this study aims to examine the the...

    Steven W. Shaw, Shao-Yu Peng, Ching-Chung Liang, Tzu-Yi Lin in Scientific Reports (2021)

  7. Article

    Open Access

    Effect of amniotic fluid stem cell transplantation on the recovery of bladder dysfunction in spinal cord-injured rats

    The effects of human amniotic fluid stem cell (hAFSC) transplantation on bladder function and molecular changes in spinal cord-injured (SCI) rats were investigated. Four groups were studied: sham and SCI plus ...

    Ching-Chung Liang, Sheng-Wen Steven Shaw, Yu-Shien Ko in Scientific Reports (2020)

  8. Article

    Open Access

    Improvement in bladder dysfunction after bladder transplantation of amniotic fluid stem cells in diabetic rats

    To examine the effects of human amniotic fluid stem cells (hAFSCs) transplantation on bladder function and molecular changes in diabetic rats, 60 female Sprague-Dawley rats were used for study. Three groups we...

    Ching-Chung Liang, Sheng-Wen Steven Shaw, Yung-Hsin Huang, Yi-Hao Lin in Scientific Reports (2018)

  9. No Access

    Article

    Outcome of coexistent overactive bladder symptoms in women with urodynamic urinary incontinence following anti-incontinence surgery

    The objective was to investigate the outcome of stress urinary incontinence (SUI) and overactive bladder (OAB) symptoms in women with urodynamic stress incontinence (USI) after transobturator sling procedures ...

    Ching-Chung Liang, Wu-Chiao Hsieh, LuLu Huang in International Urogynecology Journal (2017)

  10. No Access

    Article

    The surgical trends and time-frame comparison of primary surgery for stress urinary incontinence, 2006–2010 vs 1997–2005: a population-based nation-wide follow-up descriptive study

    The purpose of our study was to describe the surgical trends for female stress urinary incontinence (SUI) during 2006–2010, and a time-frame comparison with 1997–2005, based upon the National Health Insurance ...

    Chia-Jen Wu, Yat-Ching Tong, Sheng-Mou Hsiao in International Urogynecology Journal (2014)

  11. No Access

    Article

    How antepartum and postpartum acute urinary retention affects the function and structure of the rat bladder

    To examine the effect of acute urinary retention (AUR) on the urodynamic function and molecular structure of rat bladders in pregnancy and after parturition.

    Ching-Chung Liang, Yi-Hao Lin, Tse-Ching Chen in International Urogynecology Journal (2014)

  12. No Access

    Article

    Clinical impact of and contributing factors to urinary incontinence in women 5 years after first delivery

    This study was conducted to investigate the prevalence of and contributing factors to urinary incontinence (UI) in women 5 years after their first birth and to evaluate the associations of UI with delivery mod...

    Ching-Chung Liang, Ming-** Wu, Shu-Jen Lin in International Urogynecology Journal (2013)

  13. No Access

    Article

    Sexual function following outside-in transobturator midurethral sling procedures: a prospective study

    Midurethral tapes have shown favorable clinical outcomes for treating stress urinary incontinence (SUI), but the effects of outside-in transobturator midurethral sling procedures (TOT) on women’s sexual functi...

    Ching-Chung Liang, Ling-Hong Tseng, Tsia-Shu Lo in International Urogynecology Journal (2012)

  14. No Access

    Article

    Sexual function in women following transvaginal mesh procedures for the treatment of pelvic organ prolapse

    Synthetic mesh kits recently adopted in pelvic reconstructive surgeries have achieved great surgical efficacy, but the effects of transvaginal synthetic mesh procedures on women’s sexual function are still con...

    Ching-Chung Liang, Tsia-Shu Lo, Ling-Hong Tseng in International Urogynecology Journal (2012)

  15. No Access

    Article

    Changing trends of surgical approaches for uterine prolapse: an 11-year population-based nationwide descriptive study

    The interest of uterus-preserving surgery has been growing. Based on a nationwide database, we examined surgical procedures for uterine prolapse in Taiwan during the study period of 1997–2007, a total of 11 ye...

    Ming-** Wu, Cheng-Yu Long, Kuan-Hui Huang in International Urogynecology Journal (2012)

  16. No Access

    Article

    Lower urinary tract symptoms in primiparous women before and during pregnancy

    Lower urinary tract symptoms (LUTS), in particular urinary incontinence (UI), commonly develops during pregnancy or following delivery. This study was conducted to investigate the prevalence of the LUTS before...

    Ching-Chung Liang, Shuenn-Dhy Chang, Shu-Jen Lin in Archives of Gynecology and Obstetrics (2012)

  17. No Access

    Article

    A randomized controlled trial of antenatal pelvic floor exercises to prevent and treat urinary incontinence

    The aim of the study was to evaluate the effect of antenatal pelvic floor muscle exercise (PFME) in the prevention and treatment of urinary incontinence during pregnancy and postpartum period.

    Po-Chun Ko, Ching-Chung Liang, Shuenn-Dhy Chang in International Urogynecology Journal (2011)

  18. No Access

    Article

    Postoperative urinary outcomes in catheterized and non-catheterized patients undergoing laparoscopic-assisted vaginal hysterectomy—a randomized controlled trial

    The objective of this study is to assess the impact of bladder catheterization on the incidence of postoperative urinary tract infection (UTI) and urinary retention (PUR) following laparoscopic-assisted vagina...

    Ching-Chung Liang, Chyi-Long Lee, Ting-Chang Chang in International Urogynecology Journal (2009)

  19. No Access

    Article

    Resolution of elevated postvoid residual volumes after correction of severe pelvic organ prolapse

    We hypothesized that elevated postvoid residual volume (PVRV) would resolve postoperatively in women with severe pelvic organ prolapse (POP) and investigated risk factors that might hamper its resolution. Retr...

    Ching-Chung Liang, Ling-Hong Tseng, Shuenn-Dhy Chang in International Urogynecology Journal (2008)

  20. No Access

    Article

    Correlation of pelvic organ prolapse quantification system scores with obstetric parameters and lower urinary tract symptoms in primiparae postpartum

    This study investigated the correlation between results of the pelvic organ prolapse quantification (POPQ) system at 3 days and at 2 months postpartum with obstetric parameters and lower urinary tract symptoms...

    Ching-Chung Liang, Ling-Hong Tseng, Shang-Gwo Horng in International Urogynecology Journal (2007)

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