5 Result(s)
within
Charlotte Erpicum
English
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Article
Open AccessuPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis
The development of new lymphatic vessels occurs in many cancerous and inflammatory diseases through the binding of VEGF-C to its receptors, VEGFR-2 and VEGFR-3. The regulation of VEGFR-2/VEGFR-3 heterodimerisa...
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Article
Open AccessModeling pre-metastatic lymphvascular niche in the mouse ear sponge assay
Lymphangiogenesis, the formation of new lymphatic vessels, occurs in primary tumors and in draining lymph nodes leading to pre-metastatic niche formation. Reliable in vivo models are becoming instrumental for inv...
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Protocol
Functional Analysis of Dual-Specificity Protein Phosphatases in Angiogenesis
Therapeutic perspectives targeting angiogenesis in cancer stimulated an intense investigation of the mechanisms triggering and governing angiogenic processes. Several publications have highlighted the importan...
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Article
Open AccessDUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase
DUSP3 phosphatase, also known as V accinia-H 1 R elated (VHR) phosphatase, encoded by DUSP3/Dusp3 gene, is a relatively small member of the dual-specificity protein phosphatases. In vitro studies showed that DUSP...
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Article
Open AccessDigging deeper into lymphatic vessel formation in vitro and in vivo
Abnormal lymphatic vessel formation (lymphangiogenesis) is associated with different pathologies such as cancer, lymphedema, psoriasis and graft rejection. Lymphatic vasculature displays distinctive features t...
