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Article
Open AccessSDMA attenuates renal tubulointerstitial fibrosis through inhibition of STAT4
Renal tubulointerstitial fibrosis is the hallmark of various chronic kidney diseases. Symmetric dimethylarginine (SDMA) is an independent cardiovascular risk factor in patients with chronic kidney diseases, wh...
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Article
Open AccessA clinical randomized controlled trial: moxibustion at Laogong interval with Panax notoginseng promoted the maturation of arteriovenous fistulae
We aim to study the clinical effect of moxibustion at Laogong interval with Panax notoginseng on the short-term maturation and long-term patency of arteriovenous fistula.
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Article
Open AccessTanshinone I attenuates fibrosis in fibrotic kidneys through down-regulation of inhibin beta-A
Tanshinone I (Tan-I), an ingredient of Salvia miltiorrhiza, displays protective effects in several disease models. We aim to study the effect of Tan-I on renal fibrosis and explore its underlining mechanism.
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Article
Open AccessCatheterization in a patient with end-stage renal disease through persistent left superior vena cava: a rare case report and literature review
Persistent left superior vena cava (PLSVC) is a common vena cava malformation, and drains blood into the right atrium via the dilated coronary sinus in most cases. It is usually asymptomatic and detected incid...
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Article
Open AccessMagnesium lithospermate B improves renal hemodynamics and reduces renal oxygen consumption in 5/6th renal ablation/infarction rats
Magnesium lithospermate B (MLB) can promote renal microcirculation. The aim of the current project was to study whether MLB improves renal hemodynamics, oxygen consumption and subsequently attenuates hypoxia i...
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Article
Open AccessDRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
Here we report Digital RNA with pertUrbation of Genes (DRUG-seq), a high-throughput platform for drug discovery. Pharmaceutical discovery relies on high-throughput screening, yet current platforms have limited...
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Article
Open AccessComplete staghorn calculus in polycystic kidney disease: infection is still the cause
Kidney stones in patients with autosomal dominant polycystic kidney disease are common, regarded as the consequence of the combination of anatomic abnormality and metabolic risk factors. However, complete stag...
