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    Article

    Total parenteral nutrition impairs glucose metabolism by modifying the gut microbiome

    Total parenteral nutrition (TPN) can lead to complications, such as glucose metabolism disorders. While TPN is associated with impairments in intestinal function, the gut barrier and mucosal immunity, the rela...

    Peng Wang, Haifeng Sun, Gulisudumu Maitiabula, Li Zhang, Jianbo Yang in Nature Metabolism (2023)

  2. Article

    Open Access

    Manipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury

    In the widely used Carbon tetrachloride (CCl4)-induced acute liver injury (ALI) mouse model, hepatocytes are known to die from programmed cell death (PCD) processes including apoptosis and necroptosis. Both in vi...

    Ke Lu, Si-Yu Shen, Ou-Yang Luo, Yue Lu, Tian-Shu Shi, **g Wu in Cell Death & Disease (2022)

  3. Article

    Open Access

    MYPT1 reduction is a pathogenic factor of erectile dysfunction

    Erectile dysfunction (ED) is closely associated with smooth muscle dysfunction, but its underlying mechanisms remains incompletely understood. We here reported that the reduced expression of myosin phosphatase...

    Wei Zhao, Jie Sun, Liang-Yu Yao, Dong Hang, Ye-Qiong Li in Communications Biology (2022)

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    Article

    Photo-induced iodination of aryl halides under very mild conditions

    Aryl iodides are useful precursors in the synthesis of compounds used, for example, in the pharmaceutical and electronics industries. This protocol describes a transition metal–free, photo-induced aromatic Fin...

    Lu Li, Wenbo Liu, **aoyue Mu, Zetian Mi, Chao-Jun Li in Nature Protocols (2016)

  5. Article

    Calmodulin regulates the post-anaphase reposition of centrioles during cytokinesis

    A transient postanaphase repositioning of the centriole is found to control the completion of cytokinesis. Using a green fluorescent protein-calmodulin fusion protein as a living cell probe, we have previously...

    Yue Yue YU, Gu DAI, Fei Yan PAN, Jie CHEN, Chao Jun LI in Cell Research (2005)

  6. Article

    Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402

    Wnt signaling pathway is essential for development and tumorigenesis, however, this signaling pathway in the progress of hepatocellular carcinoma (HCC) remains unclear. In this paper, we studied the function o...

    Dong Hong ZHAO, Jian Jun HONG, Shi Ying GUO, Run Lin YANG, Jun YUAN in Cell Research (2004)