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Article
Total parenteral nutrition impairs glucose metabolism by modifying the gut microbiome
Total parenteral nutrition (TPN) can lead to complications, such as glucose metabolism disorders. While TPN is associated with impairments in intestinal function, the gut barrier and mucosal immunity, the rela...
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Article
Open AccessManipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury
In the widely used Carbon tetrachloride (CCl4)-induced acute liver injury (ALI) mouse model, hepatocytes are known to die from programmed cell death (PCD) processes including apoptosis and necroptosis. Both in vi...
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Article
Open AccessMYPT1 reduction is a pathogenic factor of erectile dysfunction
Erectile dysfunction (ED) is closely associated with smooth muscle dysfunction, but its underlying mechanisms remains incompletely understood. We here reported that the reduced expression of myosin phosphatase...
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Article
Photo-induced iodination of aryl halides under very mild conditions
Aryl iodides are useful precursors in the synthesis of compounds used, for example, in the pharmaceutical and electronics industries. This protocol describes a transition metal–free, photo-induced aromatic Fin...
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Article
Calmodulin regulates the post-anaphase reposition of centrioles during cytokinesis
A transient postanaphase repositioning of the centriole is found to control the completion of cytokinesis. Using a green fluorescent protein-calmodulin fusion protein as a living cell probe, we have previously...
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Article
Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402
Wnt signaling pathway is essential for development and tumorigenesis, however, this signaling pathway in the progress of hepatocellular carcinoma (HCC) remains unclear. In this paper, we studied the function o...