44 Result(s)
within
Chao-jun Li
English
-
Article
Open AccessAcceptorless cross-dehydrogenative coupling for C(sp3)-H heteroarylation mediated by a heterogeneous GaN/ketone photocatalyst/photosensitizer system
Alkanes are naturally abundant chemical building blocks that contain plentiful C(sp3)-H bonds. While inert, the activation of C(sp3)-H via hydrogen atom abstraction (HAT) stages an appealing approach to generate ...
-
Article
One-pot synthesis of toluene from methane and methanol catalyzed by GaN nanowire
The generation of aromatic benzene, toluene, and xylene (BTX) compounds from non-petroleum feedstocks is of particular interest for chemists in the eyes of sustainability. Herein, a novel synthesis of toluene ...
-
Article
Characteristics and driving factors of abandoned cultivated land in the hilly regions of southern China: A case study in Longnan, Jiangxi Province
The abandonment of cultivated land in southern China was gradually obvious. This research aims to provide a reference for solving the abandonment of cultivated land in hilly regions and promote rural developme...
-
Article
Open AccessThe rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice
The liver lipid metabolism of older individuals canbecome impaired and the circadian rhythm of genes involved in lipid metabolism is also disturbed. Although the link between metabolism and circadian rhythms i...
-
Article
Total parenteral nutrition impairs glucose metabolism by modifying the gut microbiome
Total parenteral nutrition (TPN) can lead to complications, such as glucose metabolism disorders. While TPN is associated with impairments in intestinal function, the gut barrier and mucosal immunity, the rela...
-
Article
Iodomethane as an organocatalyst for the aerobic ortho-selective trifluoromethylation of pyridines
Iodomethane is usually used as an electrophilic methylation reagent. Herein, we report its use as a C1 organocatalyst for the aerobic ortho-selective trifluoromethylation of pyridines in the absence of a trans...
-
Article
Open AccessManipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury
In the widely used Carbon tetrachloride (CCl4)-induced acute liver injury (ALI) mouse model, hepatocytes are known to die from programmed cell death (PCD) processes including apoptosis and necroptosis. Both in vi...
-
Article
Open AccessSelective conversion of methane to cyclohexane and hydrogen via efficient hydrogen transfer catalyzed by GaN supported platinum clusters
Non-oxidative liquefaction of methane at room temperature and ambient pressure has long been a scientific “holy grail” of chemical research. Herein, we exploit an unprecedented catalytic transformation of meth...
-
Article
Open AccessMYPT1 reduction is a pathogenic factor of erectile dysfunction
Erectile dysfunction (ED) is closely associated with smooth muscle dysfunction, but its underlying mechanisms remains incompletely understood. We here reported that the reduced expression of myosin phosphatase...
-
Article
Open AccessLight-driven transition-metal-free direct decarbonylation of unstrained diaryl ketones via a dual C–C bond cleavage
The cleavage and formation of carbon−carbon bonds have emerged as powerful tools for structural modifications in organic synthesis. Although transition−metal−catalyzed decarbonylation of unstrained diaryl keto...
-
Article
Open AccessUrinary levels of dimethoate, bisphenol A and benzo[a]pyrene in first-year students of Hohai University from different geographical regions
The objective of this study was to detect the urinary levels of dimethoate, benzo(a) pyrene (BaP), and bisphenol A (BPA) in first-year Hohai University students with different geographic origins.
-
Article
Open AccessDirect deoxygenative borylation of carboxylic acids
Carboxylic acids are readily available, structurally diverse and shelf-stable; therefore, converting them to the isoelectronic boronic acids, which play pivotal roles in different settings, would be highly ena...
-
Article
Open AccessA cross-dehydrogenative C(sp3)−H heteroarylation via photo-induced catalytic chlorine radical generation
Hydrogen atom abstraction (HAT) from C(sp3)–H bonds of naturally abundant alkanes for alkyl radical generation represents a promising yet underexplored strategy in the alkylation reaction designs since involving ...
-
Article
Open AccessC(sp3)−C(sp3) bond formation via nickel-catalyzed deoxygenative homo-coupling of aldehydes/ketones mediated by hydrazine
Aldehydes and ketones are widely found in biomass resources and play important roles in organic synthesis. However, the direct deoxygenative coupling of aldehydes or ketones to construct C(sp3)−C(sp3) bond remain...
-
Article
Open AccessEmpowering alcohols as carbonyl surrogates for Grignard-type reactions
The Grignard reaction is a fundamental tool for constructing C-C bonds. Although it is widely used in synthetic chemistry, it is normally applied in early stage functionalizations owing to poor functional grou...
-
Article
A Cu/Cinchona P,N-ligand system enabled general asymmetric C(sp3)-C(sp) coupling
-
Article
Open AccessLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
Lipid overload results in lipid redistribution among metabolic organs such as liver, adipose, and muscle; therefore, the interplay between liver and other organs is important to maintain lipid homeostasis. Her...
-
Article
Open AccessDirect dehydrogenative alkyl Heck-couplings of vinylarenes with umpolung aldehydes catalyzed by nickel
Alkenes are fundamental functionalities in nature and highly useful intermediates in organic synthesis, medicinal chemistry and material sciences. Transition-metal-catalyzed Heck couplings with organic halides...
-
Reference Work Entry In depth
Conversion of Lignin into High Value Chemical Products
-
Article
Open AccessN2H4 as traceless mediator for homo- and cross- aryl coupling
Transition-metal catalyzed couplings of aryl halides or arenes with aryl organometallics, as well as direct reductive coupling of two aryl halides, are the predominant methods to synthesize biaryls. However, s...
