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Chang-** Wu
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Article
Open AccessSimultaneous de novo calling and phasing of genetic variants at chromosome-scale using NanoStrand-seq
The successful accomplishment of the first telomere-to-telomere human genome assembly, T2T-CHM13, marked a milestone in achieving completeness of the human reference genome. The upcoming era of genome study wi...
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Open AccessPlasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease
Risk prediction for subsequent cardiovascular events remains an unmet clinical issue in patients with coronary artery disease. We aimed to investigate prognostic metabolic biomarkers by considering both shared...
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Age-adjusted Charlson Comorbidity Index as an effective tool for the choice between simultaneous or staged bilateral total knee arthroplasty
The choice between simultaneous and staged bilateral total knee arthroplasty (BTKA) remains controversial. Age-adjusted Charlson Comorbidity Index(CCI) is a promising tool for risk-stratification. We aimed to ...
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Open AccessClinical application of targeted next-generation sequencing in severe pneumonia: a retrospective review
The precise identification of the underlying causes of infectious diseases, such as severe pneumonia, is essential, and the development of next-generation sequencing (NGS) has enhanced the effectiveness of pat...
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Open AccessPsychometric validation of the Chinese Version of the stimulant relapse risk scale (SRRS) in patients with methamphetamine use disorder
Evaluating the risk of relapse is a pivotal step in the treatment of patients with methamphetamine use disorder (MUD). The 30-item Stimulant Relapse Risk Scale (SRRS) was originally developed in Japan to meet ...
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Synthesis of zwitterionic hydrogels by hydrophobic interaction and application of flexible sensors
Flexible strain sensors need to obtain a stable signal as the target undergoes random and repeated deformation. Therefore, excellent mechanical properties, adhesion properties, and electrical conductivity are ...
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The impact of photobiomodulation on sleep and life quality in hemodialysis patients: A randomized controlled trial
The quality of life (QoL) and sleep quality are closely linked to the physical and psychological health of end-stage renal disease (ESRD) patients, especially those underwent hemodialysis (HD) therapy. This st...
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Exploring the link between metformin use and adhesive capsulitis of the shoulder: a retrospective cohort study in Taiwan
The risk of adhesive capsulitis of shoulder in diabetic patients taking metformin has not been evaluated. We aimed for evaluating the relative risk of adhesive capsulitis of shoulder in diabetic patients takin...
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Open AccessDeep learning pneumoconiosis staging and diagnosis system based on multi-stage joint approach
Pneumoconiosis has a significant impact on the quality of patient survival due to its difficult staging diagnosis and poor prognosis. This study aimed to develop a computer-aided diagnostic system for the scre...
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Open AccessMyricetin mitigates motor disturbance and decreases neuronal ferroptosis in a rat model of Parkinson’s disease
Ferroptosis is an iron-dependent cell death form characterized by reactive oxygen species (ROS) overgeneration and lipid peroxidation. Myricetin, a flavonoid that exists in numerous plants, exhibits potent ant...
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Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Open AccessIntravitreal ranibizumab injection is associated with an increased risk of chronic kidney disease: a population-based study in Taiwan
Systemic vascular endothelial growth factor (VEGF) blockade has been the top adjunctive chemotherapy since 1990. Anti-VEGF therapy has also been associated with worsened renal function in some patients. Howeve...
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Validation of the constitution in Chinese medicine questionnaires with the newly developed blood-vacuity category: a rare Taiwanese case study
The concept of body constitution (BC) is a core notion in traditional Chinese medicine, used in diagnosis, treatment, and prevention; however, there is little standardization in terms of definitions and measur...
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Prescribed-time stabilization and optimization of CPS-based microgrids with event-triggered interactions
This paper investigates the problems of prescribed-time stabilization and optimization for microgrids with event-triggered interactions employing the cyber-physical system (CPS) framework. The main objective i...
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Plasmon-enhanced ultra-high photoresponse of single-wall carbon nanotube/copper/silicon near-infrared photodetectors
Single wall carbon nanotube (SWCNT)/Si heterojunction photodetectors have the advantages of high photoresponse ability and simple structure, however, their detection wavelength range are usually lower than 110...
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Open AccessA reliable authentication scheme of personal health records in cloud computing
A patient-centered personal health records system has been actively promoted in recent years. Its purpose is to maintain long-term personal records and health improvement plans. It combines a cloud computing e...
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Demographics and medical burden of osteogenesis imperfecta: a nationwide database analysis
The epidemiological data on osteogenesis imperfecta (OI) in Asia is limited. This study, representing the first comprehensive epidemiological investigation on OI in Taiwan, reveals high medical resource utiliz...
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Typhoon-Induced Ocean Waves and Stokes Drift: A Case Study of Typhoon Mangkhut (2018)
Ocean waves and Stokes drift are generated by typhoons. This study investigated the characteristics of ocean waves and wave-induced Stokes drift and their effects during Typhoon Mangkhut using European Centre ...
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Open AccessDevelo** an entrustable professional activity for providing health education and consultation in occupational therapy and examining its validity
Entrustable Professional Activities (EPA)-based assessment is easily and intuitively used in evaluating the learning outcomes of competency-based medical education (CBME). This study aimed to develop an EPA fo...
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Open AccessSearch for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...
