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ShapeMetrics: A 3D Cell Segmentation Pipeline for Single-Cell Spatial Morphometric Analysis

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  1. Article

    Open Access

    Maintenance of pluripotency-like signature in the entire ectoderm leads to neural crest stem cell potential

    The ability of the pluripotent epiblast to contribute progeny to all three germ layers is thought to be lost after gastrulation. The later-forming neural crest (NC) rises from ectoderm and it remains poorly un...

    Ceren Pajanoja, Jenny Hsin, Bradley Olinger, Andrew Schiffmacher… in Nature Communications (2023)

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  2. Article

    Open Access

    Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

    Lipid-induced toxicity is part of several human diseases, but the mechanisms involved are not fully understood. Fatty liver is characterized by the expression of different growth and tissue factors. The neurot...

    Dan Duc Pham, Céline Bruelle, Hai Thi Do, Ceren Pajanoja… in Cell Death & Disease (2019)

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  3. Article

    Open Access

    Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish

    Neurotrophins and their receptors have highly conserved evolutionary lineage in vertebrates including zebrafish. The NTRK2 receptor has two isoforms in zebrafish, Ntrk2a and Ntrk2b. The spatio-temporal express...

    Madhusmita Priyadarshini Sahu, Yago Pazos-Boubeta, Ceren Pajanoja… in Scientific Reports (2019)

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