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  1. No Access

    Article

    Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Paul Pharoah and colleagues report the results of a large genome-wide association study of ovarian cancer. They identify new susceptibility loci for different epithelial ovarian cancer histotypes and use integ...

    Catherine M Phelan, Karoline B Kuchenbaecker, Jonathan P Tyrer… in Nature Genetics (2017)

  2. No Access

    Article

    Assessing the genetic architecture of epithelial ovarian cancer histological subtypes

    Epithelial ovarian cancer (EOC) is one of the deadliest common cancers. The five most common types of disease are high-grade and low-grade serous, endometrioid, mucinous and clear cell carcinoma. Each of these...

    Gabriel Cuellar-Partida, Yi Lu, Suzanne C. Dixon, Peter A. Fasching… in Human Genetics (2016)

  3. No Access

    Article

    Identification of six new susceptibility loci for invasive epithelial ovarian cancer

    Georgia Chenevix-Trench and colleagues report meta-analyses of genome-wide association studies identifying six loci newly associated with epithelial ovarian cancer (EOC). They also test variants at the 12 know...

    Karoline B Kuchenbaecker, Susan J Ramus, Jonathan Tyrer, Andrew Lee… in Nature Genetics (2015)

  4. No Access

    Article

    Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA

    Epithelial ovarian cancer (EOC) is a heterogeneous cancer with both genetic and environmental risk factors. Variants influencing the risk of develo** the less-common EOC subtypes have not been fully investi...

    Madalene A. Earp, Linda E. Kelemen, Anthony M. Magliocco… in Human Genetics (2014)

  5. No Access

    Article

    GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

    Paul Pharoah, Joellen Schildkraut, Thomas Sellers and colleagues report a meta-analysis of genome-wide association studies for epithelial ovarian cancer and genoty** using the iCOGS array in 18,174 cases and...

    Paul D P Pharoah, Ya-Yu Tsai, Susan J Ramus, Catherine M Phelan… in Nature Genetics (2013)

  6. No Access

    Article

    Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig Bojesen, Georgia Chenevix-Trench, Alison Dunning and colleagues report common variants at the TERT-CLPTM1L locus associated with mean telomere length measured in whole blood. They also identify associations ...

    Stig E Bojesen, Karen A Pooley, Sharon E Johnatty, Jonathan Beesley… in Nature Genetics (2013)

  7. No Access

    Article

    Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

    Association studies offer a potentially powerful approach to identify genetic variants that influence susceptibility to common disease1,2,3,4, but are plagued by the impression that they are not consistently repr...

    Kirk E. Lohmueller, Celeste L. Pearce, Malcolm Pike, Eric S. Lander… in Nature Genetics (2003)